Karaciğerin Segmenter Anatomisi
Özet
Karaciğer, yaklaşık 1500 gram ağırlığıyla vücudun en büyük solid organı olup sağ üst abdominal kavitede yer alır ve dıştan Glisson kapsülü ile sarılıdır. Peritoneal uzantılar ve ligamentöz yapılar sayesinde karın içindeki konumunu koruyan organ, Cantlie çizgisi ile anatomik olarak sağ ve sol loba ayrılır. Fonksiyonel segmentasyonu temel alan Couinaud, Goldsmith ve Woodburne ile Bismuth sınıflandırma sistemleri cerrahi anatomide en sık kullanılan yöntemlerdir. Bu sistemlere göre karaciğer, her biri bağımsız bir portal pedikülden (hepatik arter, portal ven ve safra kanalı) beslenen 8 fonksiyonel segmente ayrılır. Organın kan akımının %25'i çölyak trunkustan köken alan hepatik arterden, %75'i ise süperior mezenterik ven ile splenik venin birleşmesiyle oluşan portal venden sağlanır. Hepatik arter anatomisi portal vene kıyasla daha fazla varyasyon göstermekte olup bu varyasyonlar Michels sınıflaması ile tanımlanmıştır. Venöz drenaj ise temel olarak sağ, sol ve orta hepatik venler aracılığıyla vena kava inferiora gerçekleştirilir. Karaciğerin bu segmental ve vasküler anatomisinin bilinmesi, cerrahi onkoloji ve genel cerrahi pratiklerinde rezeksiyonların güvenle uygulanması açısından kritik önem taşır.
The liver, weighing approximately 1500 grams, is the largest solid organ in the body, located in the right upper abdominal cavity and enclosed by Glisson's capsule. Secured by peritoneal attachments and ligamentous structures, the liver is divided into right and left lobes by Cantlie's line. In surgical anatomy, the classification systems of Couinaud, Goldsmith and Woodburne, and Bismuth are the most widely utilized frameworks for functional segmentation. According to these systems, the liver is divided into 8 functional segments, each supplied by an independent portal pedicle consisting of a hepatic artery, a portal vein, and a bile duct. The liver receives 25% of its blood supply from the hepatic artery originating from the celiac trunk, and 75% from the portal vein formed by the confluence of the superior mesenteric and splenic veins. The hepatic arterial anatomy exhibits significant variations compared to the portal vein, which are categorized by the Michels classification. Venous drainage is primarily directed to the inferior vena cava via the right, left, and middle hepatic veins. Understanding this detailed segmental and vascular anatomy is highly crucial for safely performing resections in surgical oncology and general surgery practices.
Referanslar
Gryspeerdt S, Van Hoe L, Marchal G, Baert AL. Evaluation of hepatic perfusion disorders with double-phase spiral CT. Radiographics 1997; 17: 337-48.
Lawrence HB. Alimentary system. In: Williams PL, Lawrence HB, Martin MB, Patricia C, Mary D. Gray’sanatomy. 38th ed. USA, 1995;1683-813.
Hess RJ. Functional anatomy of the liver. South west Med. 1969; 50(12): 226-228.
Skandalakis JE. Skandalakis Cerrahi Anatomi II: Modern Cerrahinin Embriyolojik ve Anatomik Temelleri. Başaklar C (Ed). Ankara, 2008.
Marks, W.M., R.A. Filly, and P.W. Callen, Ultrasonic anatomy of the liver: a review with new applications. J Clin Ultrasound, 1979. 7(2): p. 137-46.
Goldsmith NA, Woodburne RT. Surgical anatomy pertaining to liver resection. Surg Gynecol Obstetr 1957; 195: 310-8.
Couinaud C. Liver anatomy: portal (and suprahepatic) or biliary segmentation. DigSurg. 1999; 16 (6): 459-467.
Bismuth H. Surgical anatomy and anatomical surgery of the liver. World J Surg 1982; 6: 3-9.
Soyer P. Segmental anatomy of the liver: utility of a nomenclature accepted world wide. AJR American journal of roentgenology. 1993;161:572-3.
Healey JE Jr, Schroy PC. Anatomy of the biliary ducts within the human liver: analysis of the prevailing pattern of branchings and the major variations of the biliary ducts. AMA ArchSurg 1953;66 (5):599-616.
Jamieson GG. The anatomy of general surgical operations. 2nd edition. Edinburgh (NY): Churchill Livingstone/Elsevier; 2006. pp. 8–23.
MacSween RNM, Burt AD, Portmann BC, Ishak KG, Scheuer PJ, Anthony PP. Pathology of the liver. London: Churchill Livingstone; 2002. p. 1-66.
J. C. On a new arrangement of the right and left lobes of the liver. Proc Anat Soc Great Britain Ireland32:4-9.
Terminologia anatomica: international anatomical terminology. FCAT. Thieme, Stuttgart, New York; 1998. p. 54-6.
vanLeeuwen MS, Fernandez MA, van Es HW, Stokking R, Dillon EH, Feldberg MA. Variations in venous and segmental anatomy of the liver: two and three-dimensional MR imaging in healthy volunteers. AJR Am J Roentgenol 1994; 162: 1337-45.
Kaufman J, Lee MJ. . Vascular&interventional radiology. 1st ed. Michigan, USA, Mosby. 2004.
Michels NA: Newer anatomy of the liver and its variant blood supply and collateral circulation. Am J Surg 1966; 112: 337-347.
Daseler E, Anson B, Hambley W, Reiman A. Cystic artery and constituents of the hepatic pedicle. Surg Gynecol Obstet 1947;85:47.
Van Damme JP. Behavioral anatomy of the abdominal arteries. SurgClin North Am 1993;73 (4):699-725.
Ugurel MS, Battal B, Bozlar U, Nural MS, Tasar M, Ors F et al. Anatomical variations of hepatic arterial system, coeliac trunk and renal arteries: an analysis with multidetector CT angiography. Br J Radiol 2010; 83: 661-7.
Atasoy C, Ozyurek E. Prevalence and types of main and right portal vein branching variations on MDCT. AJR Am J Roentgenol 2006; 187: 676–81.
Ger R. Surgical anatomy of the liver. SurgClin North Am. 1989;69(2):179–192.
Delattre JF, Avisse C, Flament JB. Anatomic basis of hepatic surgery. SurgClin North Am 2000;80(1):345-62.
Nakamura S, Tsuzuki T. Surgical anatomy of the hepatic veins and the inferior vena cava.Surg Gynecol Obstet 1981;152 (1):43-50.
Lafortune M, Madore F, Patriquin H, Breton G. Segmental anatomy of the liver: a sonographic approach to the Couinaud nomenclature. Radiology 1991; 181: 443-448
Soyer P, Heath D, Bluemke DA, Choti MA, Kuhlman JE, Reichle R, et al. Three-dimensional helical CT of intrahepatic venous structures: comparison of three rendering techniques. J Comput Assist Tomogr 1996; 20: 122-7.
Whitmore I. Terminologia anatomica: new terminology for the new anatomist. Anatom Rec (New Anat) 1999;257:50-3.