Kasık Fıtığında Prostetik Materyaller

Yazarlar

Ahmet Çakmak

Özet

Kasık fıtığı tedavisinde son 70 yıldır yaygın olarak kullanılan sentetik protez materyalleri (meshler), nüks oranlarını önemli ölçüde düşürerek altın standart haline gelmiştir. Günümüzde tercih edilen materyaller polipropilen, polyester, PTFE ve ePTFE olmak üzere dört ana hammaddeye dayanmakta ve cerrahlara geniş bir çeşitlilik sunmaktadır. İdeal bir meshin kimyasal olarak inert, mekanik gerilimlere dayanıklı, esnek, enfeksiyona dirençli olması ve doku ile fibroblastik aktivite uyarımı üzerinden sağlıklı bütünleşmesi beklenir. Sentetik meshler gözenek boyutu, lif kalınlığı ve ağırlıklarına göre ağır veya hafif olarak sınıflandırılır; hafif meshler daha az yabancı cisim reaksiyonuna yol açıp hasta konforunu artırırken, nüks ve komplikasyon oranlarında ağır meshlerle benzer sonuçlar göstermektedir. Son yıllarda, ameliyat sonrası kronik kasık ağrısını azaltmak amacıyla dikişli fiksasyon yerine fibrin yapıştırıcılar ve kendiliğinden kavramalı (self-gripping) yeni nesil meshler geliştirilmiştir. Sonuç olarak, mesh seçiminde hastanın yaşı, defekt boyutu ve maliyet gibi kriterler rol oynasa da cerrahın deneyimi ve teknik becerisi ameliyat başarısını doğrudan etkileyen en kritik unsurdur.

Synthetic prosthetic materials (meshes), which have been widely used in groin hernia treatment for the last 70 years, have become the gold standard by significantly reducing recurrence rates. Today, the preferred materials are based on four main raw materials—polypropylene, polyester, PTFE, and ePTFE—offering a wide variety to surgeons. An ideal mesh is expected to be chemically inert, resistant to mechanical stress, flexible, infection-resistant, and soundly integrated with the tissue through the stimulation of fibroblastic activity. Synthetic meshes are classified as heavyweight or lightweight depending on their pore size, filament thickness, and weight; lightweight meshes induce less foreign body reaction and improve patient comfort, while demonstrating similar results to heavyweight meshes regarding recurrence and complication rates. In recent years, in order to reduce postoperative chronic groin pain, fibrin glues and self-gripping next-generation meshes have been developed instead of sutured fixation. Consequently, although criteria such as patient age, defect size, and cost play a role in mesh selection, the surgeon's experience and technical skill remain the most critical factors directly affecting surgical success.

Referanslar

Rutkow IM. Demographic and socioeconomic aspects of hernia repair in the United States in 2003. Surgical Clinics. 2003 Oct 1;83(5):1045-51.

EU Hernia Trialists Collaboration. Repair of groin hernia with synthetic mesh: meta-analysis of randomized controlled trials. Annals of surgery. 2002 Mar;235(3):322.

Morgan M, Reynolds A, Swan AV, Beech R, Devlin HB. Are current techniques of inguinal hernia repair optimal? A survey in the United Kingdom. Annals of the Royal College of Surgeons of England. 1991 Nov;73(6):341.

Atabek U, Spence RK, Pello M, Alexander J, Story L, Camishion RC. A survey of preferred approach to inguinal hernia repair: laparoscopic or inguinal incision?. The American surgeon. 1994 Apr 1;60(4):255-8.

Procter L, Falco EE, Fisher JP, Roth JS. Abdominal wall hernias and biomaterials. InBioengineering research of chronic wounds 2009 (pp. 425-447). Springer, Berlin, Heidelberg.

Cozad MJ, Grant DA, Bachman SL, Grant DN, Ramshaw BJ, Grant SA. Materials characterization of explanted polypropylene, polyethylene terephthalate, and expanded polytetrafluoroethylene composites: spectral and thermal analysis. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2010 Aug;94(2):455-62.

Grevious MA, Cohen M, Shah SR, Rodriguez P. Structural and functional anatomy of the abdominal wall. Clinics in Plastic Surgery. 2006 Apr 1;33(2):169-79.

Binnebösel M, Von Trotha KT, Lynen Jansen P, Conze J, Neumann UP, Junge K. Biocompatibility of prosthetic meshes in abdominal surgery. InSeminars in immunopathology 2011 May (Vol. 33, No. 3, pp. 235-243). Springer-Verlag.

Hamer-Hodges DW, Scott NB. Surgeon's workshop. Replacement of an abdominal wall defect using expanded PTFE sheet (Gore-tex). Journal of the Royal College of Surgeons of Edinburgh. 1985 Feb;30(1):65-7.

Pereira-Lucena CG, Artigiani-Neto R, Lopes-Filho GJ, Frazao CV, Goldenberg A, Matos D, Linhares MM. Experimental study comparing meshes made of polypropylene, polypropylene+ polyglactin and polypropylene+ titanium: inflammatory cytokines, histological changes and morphometric analysis of collagen. Hernia. 2010 Jun;14(3):299-304.

Amid PK. Classification of biomaterials and their related complications in abdominal wall hernia surgery. Hernia. 1997 May;1(1):15-21.

Brown CN, Finch JG. Which mesh for hernia repair?. The Annals of The Royal College of Surgeons of England. 2010 May;92(4):272-8.

Koch A, Bringman S, Myrelid P, Smeds S, Kald A. Randomized clinical trial of groin hernia repair with titanium-coated lightweight mesh compared with standard polypropylene mesh. Journal of British Surgery. 2008 Oct;95(10):1226-31.

Arnold MR, Coakley KM, Fromke EJ, Groene SA, Prasad T, Colavita PD, Augenstein VA, Kercher KW, Heniford BT. Long-term assessment of surgical and quality-of-life outcomes between lightweight and standard (heavyweight) three-dimensional contoured mesh in laparoscopic inguinal hernia repair. Surgery. 2019 Apr 1;165(4):820-4.

Bakker WJ, Aufenacker TJ, Boschman JS, Burgmans JP. Lightweight mesh is recommended in open inguinal (Lichtenstein) hernia repair: A systematic review and meta-analysis. Surgery. 2020 Mar 1;167(3):581-9.

Currie A, Andrew H, Tonsi A, Hurley PR, Taribagil S. Lightweight versus heavyweight mesh in laparoscopic inguinal hernia repair: a meta-analysis. Surgical endoscopy. 2012 Aug;26(8):2126-33.

Stavert B, Chan DL, Ozmen J, Loi K. Laparoscopic totally extra‐peritoneal groin hernia repair with self‐gripping polyester mesh: a series of 780 repairs. ANZ Journal of Surgery. 2019 Oct;89(10):1261-4.

Swedish Hernia Data Base the Danish Hernia Data Base Bay-Nielsen M morten. bay. nielsen@ hh. hosp. dk Nilsson E Nordin P Kehlet H. Chronic pain after open mesh and sutured repair of indirect inguinal hernia in young males. Journal of British Surgery. 2004 Oct;91(10):1372-6.

Fountain Y. The chronic pain policy coalition. The Bulletin of the Royal College of Surgeons of England. 2006 Sep 1;88(8):279-.

Bringman S, Wollert S, Österberg J, Smedberg S, Granlund H, Heikkinen TJ. Three-year results of a randomized clinical trial of lightweight or standard polypropylene mesh in Lichtenstein repair of primary inguinal hernia. Journal of British Surgery. 2006 Sep;93(9):1056-9.

Canonico S, Benevento R, Perna G, Guerniero R, Sciaudone G, Pellino G, Santoriello A, Selvaggi F. Sutureless fixation with fibrin glue of lightweight mesh in open inguinal hernia repair: effect on postoperative pain: a double-blind, randomized trial versus standard heavyweight mesh. Surgery. 2013 Jan 1;153(1):126-30.

de Goede B, Klitsie PJ, Van Kempen BJ, Timmermans L, Jeekel J, Kazemier G, Lange JF. Meta-analysis of glue versus sutured mesh fixation for Lichtenstein inguinal hernia repair. Journal of British Surgery. 2013 May;100(6):735-42.

Pandanaboyana S, Mittapalli D, Rao A, Prasad R, Ahmad N. Meta-analysis of self-gripping mesh (Progrip) versus sutured mesh in open inguinal hernia repair. The Surgeon. 2014 Apr 1;12(2):87-93.

Sayfalar

49-57

Gelecek

20 Temmuz 2022

Lisans

Lisans