İnguinodini'de Nonoperatif Hasta Yönetimi

Yazarlar

Yasin Güneş
https://orcid.org/0000-0003-3951-0721

Özet

Kasık fıtığı onarımı sonrası 3 aydan uzun süren patolojik ağrılar inguinodini (kronik kasık ağrısı) olarak adlandırılır. Genellikle nöropatik karakterde olan bu durumun etyolojisinde ilioinguinal, iliohipogastrik, genitofemoral ve lateral femoral kutanöz sinirler yer alır. Genç yaş, kadın cinsiyet, ameliyat öncesi ağrı varlığı, fıtığın tekrarlaması, deneyimsiz cerrahlar, açık fıtık onarımı ve yüksek yoğunluklu mesh kullanımı postoperatif nevralji için temel risk faktörleridir. Tanı; klinik öykü, fizik muayene, bıçak saplanır tarzda ağrı, duyusal algıda bozulma ve tanısal periferik sinir blokajı ile konur; görüntüleme yöntemleri ise nöropatik olmayan nedenleri dışlamak için kullanılır. Ağrıyı önlemek adına laparoskopik cerrahi seçimi, sinirlerin intraoperatif olarak tanımlanması ve korunması, hafif mesh kullanımı ve fibrin yapıştırıcılar ile atravmatik sabitleme önerilmektedir. Tedavi süreci multimodal ve multidisipliner bir yaklaşım gerektirir. Farmakolojik tedavide antikonvülzanlar (gabapentin, pregabalin), antidepresanlar, topikal ajanlar ve opioidler tercih edilmektedir. İlaçların kalıcı çözüm sunamadığı durumlarda, ultrasonografi eşliğinde uzun etkili lokal anestezik ve glukokortikoid enjeksiyonunu içeren sinir blokları uygulanır. Tekrarlayan bloklara yanıt vermeyen inatçı vakalarda ise kimyasal nöroliz, kriyoablasyon veya radyofrekans ablasyon gibi sinir ablasyonu yöntemleri ile inatçı ağrılarda nöromodülasyon cihazları devreye girmektedir.

Pathological pain lasting longer than 3 months after inguinal hernia repair is defined as inguinodynia (chronic groin pain). This condition is generally neuropathic, and the ilioinguinal, iliohypogastric, genitofemoral, and lateral femoral cutaneous nerves are involved in its etiology. Young age, female gender, preoperative pain, recurrent hernia, inexperienced surgeons, open repair, and heavyweight mesh usage are main risk factors for postoperative neuralgia. Diagnosis is established through clinical history, physical examination, stabbing pain, sensory impairment, and diagnostic nerve blocks, while imaging is used to exclude non-neuropathic causes. To prevent pain, laparoscopic surgery, intraoperative nerve identification, lightweight mesh, and atraumatic fixation with fibrin glue are recommended. Management requires a multimodal and multidisciplinary approach. Pharmacological treatments include anticonvulsants (gabapentin, pregabalin), antidepressants, topical agents, and opioids. When medications provide temporary relief, ultrasound-guided nerve blocks with local anesthetics and glucocorticoids are performed. For intractable cases resistant to repetitive blocks, nerve ablation methods such as chemical neurolysis, cryoablation, or radiofrequency ablation are utilized, while neuromodulation devices are considered for persistent pain.

Referanslar

Hakeem A, Shanmugam V. Inguinodynia following Lichtenstein tension-free hernia repair: a review. World journal of gastroenterology: WJG. 2011 Apr 14;17(14):1791.

Morales-Barrios J, Flores-Rangel GA, Chávez-Villacaña E. Inguinodynia. Revista Mexicana de Anestesiología. 2016 Jun 27;39(2):122-8.

Prasad D, Patel Y. A study of incidence of inguinodynia in inguinal hernias repair at a tertiary center. International Surgery Journal. 2020 Aug 27;7(9):2985-90.

Rao J, Bottros M. Inguinodynia: Nonoperative Management. InSurgical Principles in Inguinal Hernia Repair 2018 (pp. 99-108). Springer, Cham.

Barbosa CD, Oliveira DC, DE-Melo-Delgado NM, Mafra JG, Santos RS, Moreira WC. Inguinodynia: review of predisposing factors and management. Revista do Colégio Brasileiro de Cirurgiões. 2021 Jan 8;47.

Kehlet H, Jensen TS, Woolf CJ. Persistent postsurgical pain: risk factors and prevention. The lancet. 2006 May 13;367(9522):1618-25.

Tverskoy M, Cozacov C, Ayache M, Bradley Jr EL, Kissin I. Postoperative pain after inguinal herniorrhaphy with different types of anesthesia. Anesthesia & Analgesia. 1990 Jan 1;70(1):29-35.

Donati M, Brancato G, Giglio A, Biondi A, Basile F, Donati A. Incidence of pain after inguinal hernia repair in the elderly. A retrospective historical cohort evaluation of 18-years’ experience with a mesh & plug inguinal hernia repair method on about 3000 patients. BMC surgery. 2013 Oct;13(2):1-6.

O'dwyer PJ, Kingsnorth AN, Molloy RG, Small PK, Lammers B, Horeyseck G. Randomized clinical trial assessing impact of a lightweight or heavyweight mesh on chronic pain after inguinal hernia repair. Journal of British Surgery. 2005 Feb;92(2):166-70.

Bringman S, Wollert S, Österberg J, Smedberg S, Granlund H, Heikkinen TJ. Three-year results of a randomized clinical trial of lightweight or standard polypropylene mesh in Lichtenstein repair of primary inguinal hernia. Journal of British Surgery. 2006 Sep;93(9):1056-9.

Fränneby U, Sandblom G, Nordin P, Nyrén O, Gunnarsson U. Risk factors for long-term pain after hernia surgery. Annals of surgery. 2006 Aug;244(2):212.

Bay-Nielsen M, Perkins FM, Kehlet H. Pain and functional impairment 1 year after inguinal herniorrhaphy: a nationwide questionnaire study. Annals of surgery. 2001 Jan;233(1):1.

Poobalan AS, Bruce J, King PM, Chambers WA, Krukowski ZH, Smith WC. Chronic pain and quality of life following open inguinal hernia repair. Journal of British Surgery. 2001 Aug;88(8):1122-6.

Condon RE. Groin pain after hernia repair. Annals of surgery. 2001 Jan;233(1):8.

Reinpold W. Risk factors of chronic pain after inguinal hernia repair: a systematic review. Innovative surgical sciences. 2017 Jun 1;2(2):61-8.

Andercou O, Olteanu G, Stancu B, Mihaileanu F, Chiorescu S, Dorin M. Risk factors for and prevention of chronic pain and sensory disorders following inguinal hernia repair. Annali italiani di chirurgia. 2019 Feb;90:442-6.

Konschake M, Zwierzina M, Moriggl B, Függer R, Mayer F, Brunner W, Schmid T, Chen DC, Fortelny R. The inguinal region revisited: the surgical point of view. Hernia. 2020 Aug;24(4):883-94.

Chinchilla-Hermida PA, Baquero-Zamarra DR, Guerrero-Nope C, Bayter-Mendoza EF. Incidence of chronic post-surgical pain and its associated factors in patients taken to inguinal hernia repair. Colombian Journal of Anestesiology. 2017 Dec;45(4):291-9.

Zwaans WA, Verhagen T, Roumen RM, Scheltinga MR. Factors determining outcome after surgery for chronic groin pain following a Lichtenstein hernia repair. World journal of surgery. 2015 Nov;39(11):2652-62.

Crompton JG, Dawes AJ, Donald GW, Livhits MJ, Chandler CF. Perineural bupivacaine injection reduces inguinodynia after inguinal hernia repair. Surgery. 2016 Dec 1;160(6):1528-32.

Öberg S, Andresen K, Klausen TW, Rosenberg J. Chronic pain after mesh versus nonmesh repair of inguinal hernias: a systematic review and a network meta-analysis of randomized controlled trials. Surgery. 2018 May 1;163(5):1151-9.

Bakker WJ, Aufenacker TJ, Boschman JS, Burgmans JP. Lightweight mesh is recommended in open inguinal (Lichtenstein) hernia repair: A systematic review and meta-analysis. Surgery. 2020 Mar 1;167(3):581-9.

Negro P, Basile F, Brescia A, Buonanno GM, Campanelli G, Canonico S, Cavalli M, Corrado G, Coscarella G, Di Lorenzo N, Falletto E. Open tension-free Lichtenstein repair of inguinal hernia: use of fibrin glue versus sutures for mesh fixation. Hernia. 2011 Feb;15(1):7-14.

Lange JF, Wijsmuller AR, Van Geldere D, Simons MP, Swart R, Oomen J, Kleinrensink GJ, Jeekel J, Lange JF. Feasibility study of three-nerve-recognizing Lichtenstein procedure for inguinal hernia. Journal of British Surgery. 2009 Oct;96(10):1210-4.

Alfieri S, Rotondi F, Di Giorgio A, Fumagalli U, Salzano A, Di Miceli D, Ridolfini MP, Sgagari A, Doglietto G, Groin Pain Trial Group. Influence of preservation versus division of ilioinguinal, iliohypogastric, and genital nerves during open mesh herniorrhaphy: prospective multicentric study of chronic pain. Annals of surgery. 2006 Apr;243(4):553.

Barazanchi AW, Fagan PV, Smith BB, Hill AG. Routine neurectomy of inguinal nerves during open onlay mesh hernia repair. Annals of surgery. 2016 Jul 1;264(1):64-72.

Thomassen I, Van Suijlekom JA, Van De Gaag A, Ponten JE, Nienhuijs SW. Ultrasound-guided ilioinguinal/iliohypogastric nerve blocks for chronic pain after inguinal hernia repair. Hernia. 2013 Jun;17(3):329-32.

Wong AK, Ng AT. Review of Ilioinguinal Nerve Blocks for Ilioinguinal Neuralgia Post Hernia Surgery. Current Pain and Headache Reports. 2020 Dec;24(12):1-5.

Gofeld M, Christakis M. Sonographically guided ilioinguinal nerve block. Journal of ultrasound in medicine. 2006 Dec;25(12):1571-5.

Demirci A, Efe EM, Türker G, Gurbet A, Kaya FN, Anil A, Çimen İ. Bloqueio dos nervos ílio-hipogástrico/ilioinguinal em correção de hérnia inguinal para tratamento da dor no pós-operatório: comparação entre a técnica de marcos anatômicos e a guiada por ultrassom. Revista Brasileira de Anestesiologia. 2014 Sep;64:350-6.

Trainor D, Moeschler S, Pingree M, Hoelzer B, Wang Z, Mauck W, Qu W. Landmark-based versus ultrasound-guided ilioinguinal/iliohypogastric nerve blocks in the treatment of chronic postherniorrhaphy groin pain: a retrospective study. Journal of Pain Research. 2015;8:767.

Parris D, Fischbein N, Mackey S, Carroll I. A novel CT-guided transpsoas approach to diagnostic genitofemoral nerve block and ablation. Pain Medicine. 2010 May 1;11(5):785-9.

Fanelli RD, DiSiena MR, Lui FY, Gersin KS. Cryoanalgesic ablation for the treatment of chronic postherniorrhaphy neuropathic pain. Surgical Endoscopy and Other Interventional Techniques. 2003 Feb;17(2):196-200.

Werner MU, Bischoff JM, Rathmell JP, Kehlet H. Pulsed radiofrequency in the treatment of persistent pain after inguinal herniotomy: a systematic review. Regional Anesthesia & Pain Medicine. 2012 May 1;37(3):340-3.

Sayfalar

167-178

Gelecek

20 Temmuz 2022

Lisans

Lisans