Pnömotoraks

Yazarlar

Muharrem Özkaya
https://orcid.org/0000-0002-3507-1349

Özet

Pnömotoraks, plevral boşlukta hava birikmesiyle karakterize, akciğerin çökmesine yol açan ve solunumu bozan bir durumdur. Etiyolojik olarak primer/sekonder spontan ve travmatik; patofizyolojik olarak ise açık, kapalı ve tansiyon pnömotoraks olarak sınıflandırılır. Altta yatan bir akciğer hastalığı olmadan gençlerde görülen primer spontan pnömotoraks (PSP) subplevral bleblerin rüptüründen kaynaklanırken, yaşlılarda KOAH gibi nedenlerle sekonder spontan pnömotoraks (SSP) gelişir. Son dönemde COVID-19 hastalarında da invaziv mekanik ventilasyona bağlı sekonder pnömotoraks insidansında artış gözlenmiştir. Tanı aşamasında göğüs ağrısı ve nefes darlığı en sık semptomlar olup, teşhis ayakta çekilen inspirium göğüs radyografisi veya bilgisayarlı tomografi ile doğrulanır. Tedavi yaklaşımı pnömotoraksın boyutundan ziyade hastanın klinik durumuna göre belirlenir. Asemptomatik küçük PSP vakalarında oksijen desteği ve yatak istirahati içeren konservatif gözlem tercih edilirken, semptomatik veya geniş vakalarda iğne aspirasyonu ya da tüp torakostomisi (kapalı su altı drenajı) uygulanır. Tekrarlayan ataklar veya uzamış hava kaçaklarında ise bül rezeksiyonu ve plevral boşluğun obliterasyonunu (plörektomi, abrazyon veya talk plöredezi) hedefleyen cerrahi müdahaleler (VATS veya torakotomi) elzemdir. Tansiyon pnömotoraks ise acil iğne dekompresyonu gerektiren kritik bir tıbbi acildir.

Pneumothorax is defined as the accumulation of air within the pleural space, leading to partial or complete lung collapse and severely impairing respiratory gas exchange. It is etiologically classified into spontaneous (primary and secondary) and traumatic, and pathophysiologically into open, closed, or tension pneumothorax. Primary spontaneous pneumothorax (PSP) typically affects young individuals without underlying lung diseases, primarily due to subpleural bleb rupture or pleural porosity. Conversely, secondary spontaneous pneumothorax (SSP) occurs in older patients with pre-existing conditions like COPD, significantly increasing mortality. Recently, hospitalized COVID-19 patients on invasive mechanical ventilation have shown a notable incidence of secondary pneumothorax. Clinical presentation involves sharp chest pain and dyspnea, with diagnosis confirmed via inspiratory chest X-rays or computed tomography. Management strategy relies heavily on clinical symptoms rather than size alone. Small, asymptomatic PSP cases are managed conservatively with observation and oxygen therapy, which accelerates air resorption. For symptomatic or large pneumothoraces, intervention involves needle aspiration or tube thoracostomy. In cases of recurrence, persistent air leaks, or bilateral presentations, surgical options such as video-assisted thoracoscopic surgery (VATS) or thoracotomy are indicated to perform wedge resection and pleural obliteration (pleurectomy, mechanical abrasion, or chemical pleurodesis). Tension pneumothorax remains a life-threatening medical emergency requiring immediate needle decompression.

Referanslar

Kaya SO, Karatepe M, Tok T, Onem G, Dursunoglu N, Goksin I. Were pneumothorax and its management known in 15th-century Anatolia? Tex Hear Inst J. 2009;36(2):152–153.

Uzel I. Cerrahiyyetu’l Haniyye. 1st ed. Ankara: Turk Tarih Kurumu Yayinlari (Turkish Historical Society); 1992.

Batirel HF, Yüksel M. Thoracic surgery techniques of Serefeddin Sabuncuoglu in the fifteenth century. Ann Thorac Surg. 1997

DERBES VJ, MITCHELL RE. Hermann Boerhaave’s Atrocis, nec descripti prius, morbi historia, the first translation of the classic case report of rupture of the esophagus, with annotations. Bull Med Libr Assoc. 1955;43(2):217–240.

Itard JM. Dissertation sur le pneumo-thorax ou les congestions gazeuses qui déforment dans la poitrine. 1803.

Laennec R. De l’Auscultation Médiate ou Traité du Diagnostic des Maladies des Poumons et du Coeur. Paris: J.-A. Brosson et J.-S. Chaudé; 1819.

Kjaergaard H. Spontaneous pneumothorax in the apparently healthy. Acta Med Scand. 1932;43:1–15.

Venuta F, Diso D, Rendina E. Pneumothorax. In: LoCicero III J, Feins R, Colson Y, Rocco G, editors. Shield Gen Thorac Surg. 8th ed. Philadelphia: Wolters Kluwer; 2019. p. 1473–93.

Gupta D, Hansell A, Nichols T, Duong T, Ayres JG, Strachan D. Epidemiology of pneumothorax in England. Thorax. 2000;55(8):666–671.

Bobbio A, Dechartres A, Bouam S, et al. Epidemiology of spontaneous pneumothorax: Gender-related differences. Thorax. 2015;70(7):653–658.

Olesen WH, Titlestad IL, Andersen PE, Lindahl-Jacobsen R, Licht PB. Incidence of primary spontaneous pneumothorax: a validated, register-based nationwide study. ERJ Open Res. 2019;5(2):00022–02019.

Lu H, Stratton CW, Tang YW. Outbreak of pneumonia of unknown etiology in Wuhan, China: The mystery and the miracle. J Med Virol. 2020;92(4):401–402. doi: 10.1002/jmv.25678.

Hui DS, I Azhar E, Madani TA, et al. The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, China. Int J Infect Dis. 2020;91(2020):264–266.

Chong WH, Saha BK, Hu K, Chopra A. The incidence, clinical characteristics, and outcomes of pneumothorax in hospitalized COVID-19 patients: A systematic review. Hear Lung. Elsevier Inc.; 2021;50(5):599–608.

Geraci TC, Williams D, Chen S, et al. Incidence, Management, and Outcomes of Patients with COVID-19 and Pneumothorax. Ann Thorac Surg. The Society of Thoracic Surgeons; 2021;Baskıda.

Morrison PJ, Lowry RC, Nevin NC. Familial primary spontaneous pneumothorax consistent with true autosomal dominant inheritance. Thorax. 1998;53(2):151–152.

Bense L, Eklund G, Wiman LG. Bilateral bronchial anomaly. A pathogenetic factor in spontaneous pneumothorax. Am Rev Respir Dis. 1992;146(2):513–516.

Noppen M, Dekeukeleire T, Hanon S, et al. Fluorescein-enhanced autofluorescence thoracoscopy in patients with primary spontaneous pneumothorax and normal subjects. Am J Respir Crit Care Med. 2006;174(1):26–30.

Fujino S, Inoue S, Tezuka N, et al. Physical development of surgically treated patients with primary spontaneous pneumothorax. Chest. The American College of Chest Physicians; 1999;116(4):899–902.

Withers CJN, Fishback CME, Paul C, Kiehl V, Joseph LTC, Hannon L. Spontaneous pneumothorax. Suggested etiology and comparison of treatment methods. Am J Surg. 1964;108:772–776.

Coxson HO, Chan IHT, Mayo JR, Hlynsky J, Nakano Y, Birmingham CL. Early emphysema in patients with anorexia nervosa. Am J Respir Crit Care Med. 2004;170(7):748–752.

Noppen M. Spontaneous pneumothorax: Epidemiology, pathophysiology and cause. Eur Respir Rev. 2010;19(117):217–219.

Neptune ER, Frischmeyer PA, Arking DE, et al. Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome. Nat Genet. 2003;33(3):407–411.

Hatz RA, Kaps MF, Meimarakis G, Loehe F, Müller C, Fürst H. Long-term results after video-assisted thoracoscopic surgery for first- time and recurrent spontaneous pneumothorax. Ann Thorac Surg. 2000;70(1):253–257.

Körner H, Andersen KS, Stangeland L, Ellingsen I, Engedal H. Surgical treatment of spontaneous pneumothorax by wedge resection without pleurodesis or pleurectomy. Eur J Cardio-thoracic Surg. 1996;10(8):656–659.

Horio H, Nomori H, Kobayashi R, Naruke T, Suemasu K. Impact of additional pleurodesis in video-assisted thoracoscopic bullectomy for primary spontaneous pneumothorax. Surg Endosc Other Interv Tech. 2002;16(4):630–634.

Noppen M. Management of primary spontaneous pneumothorax. Curr Opin Pulm Med. 2003;9(4):272–275. doi: 10.1097/00063198-200307000-00005.

Radomsky J, Becker HP, Hartel W. Pleuraporositat beim idiopatischen spontanpneumothorax [Pleural porosity in idiopathic spontaneous pneumothorax]. Pneumologie. 1989;43(5):250–253.

Masshof W, Hofer W. Zur pathologie der sogenannten idiopatischen spontanpneumothorax [Pathology of so-called idiopathic spontaneous pneumothorax. Dtsch Med Wochenschr. 1973;98:801–805.

Ohata M, Suzuki H. Pathogenesis of spontaneous pneumothorax. With special reference to the ultrastructure of emphysematous bullae. Chest. The American College of Chest Physicians; 1980;77(6):771–776.

Verschoor AJ, Gelderblom H. Pneumothorax as adverse event in patients with lung metastases of soft tissue sarcoma treated with pazopanib: a single reference centre case series. Clin Sarcoma Res. Springer Nature; 2014;4(1).

Nakamura H, Konishiike J, Sugamura A, Takeno Y. Epidemiology of spontaneous pneumothorax in women. Chest. The American College of Chest Physicians; 1986;89(3):378–382.

Bove AA. Medical disorders related to diving. J Intensive Care Med. 2002;17(2):75–86.

White DC, D’Amico TA. Radiofrequency ablation for primary lung cancer and pulmonary metastases. Clin Lung Cancer. Elsevier Inc.; 2008;9(1):16–23.

Su JW, Lim CH, Chua YL. Bilateral pneumothoraces as a complication of acupuncture. Singapore Med J. 2007;48(1):32–33.

Kozacı N, Çavuşoğlu Yalçın N, Özkaya M, Kırpat V, Çelik A. A Rare Complication Caused by Dry Needling Method: Tension Pneumothorax. Respir Case Reports. 2017;6(3):145–148.

Weng W, DeCrosta DJ, Zhang H. Tension pneumothorax during one-lung ventilation: A case report. J Clin Anesth. 2002;14(7):529–531.

Rhea JT, DeLuca SA, Greene RE. Determining the size of pneumothorax in the upright patient. Radiology. 1982;144:733–736.

Hoi K, Turchin B, Kelly AM. How accurate is the Light index for estimating pneumothorax size? Australas Radiol. 2007;51(2):196–198.

Collins CD, Lopez A, Mathie A, Wood V, Jackson JE, Roddie ME. Quantification of pneumothorax size on chest radiographs using interpleural distances: Regression analysis based on volume measurements from helical CT. Am J Roentgenol. 1995;165(5):1127–1130.

Schramel FMNH, Postmus PE, Vanderschueren RGJRA. Current aspects of spontaneous pneumothorax. Eur. Respir. J. 1997. p. 1372–1379. doi: 10.1183/09031936.97.10061372.

Walker SP, Bibby AC, Halford P, Stadon L, White P, Maskell NA. Recurrence rates in primary spontaneous pneumothorax: A systematic review and meta-analysis. Eur Respir J. 2018;52(3):1–10.

Kelly AM, Loy J, Tsang AYL, Graham CA. Estimating the rate of re-expansion of spontaneous pneumothorax by a formula derived from computed tomography volumetry studies. Emerg Med J. 2006;23(10):780–782.

Northfield TC. Oxygen therapy for spontaneous pneumothorax. Br Med J. 1971;4(5779):86.

Chen JS, Hsu HH, Kuo SW, Huang PM, Lee JM, Lee YC. Management of recurrent primary spontaneous pneumothorax after thoracoscopic surgery: should observation, drainage, redo thoracoscopy, or thoracotomy be used? Surg Endosc. 2009;23(11):2438–2444.

Hernandez MC, El Khatib M, Prokop L, Zielinski MD, Aho JM. Complications in tube thoracostomy: Systematic review and meta-analysis. J Trauma Acute Care Surg. 2018;85(2):413–419.

Fang H, Xu L, Zhu F, Xia Z. Re-expansion pulmonary edema post-pneumothorax. Burn Trauma. 2020;8:1–3.

Aujayeb A, Green NJ. Re-expansion pulmonary oedema in pneumothorax. BMJ Case Rep. 2019;12(3):1–2.

Bauman MH, Strange C, Heffner JE, et al. Management of spontaneous pneumothorax: An American College of Chest Physicians Delphi Consensus Statement. Chest. 2001;119(2):590–602.

Vanderschueren RGJRA. The role of thoracoscopy in the evaluation and management of pneumothorax. Lung. Springer-Verlag; 1990;168(1):1122–1125.

Barker A, Maratos EC, Edmonds L, Lim E. Recurrence rates of video-assisted thoracoscopic versus open surgery in the prevention of recurrent pneumothoraces: a systematic review of randomised and non-randomised trials. Lancet. 2007;370(9584):329–335.

MacDuff A, Arnold A, Harvey J. Management of spontaneous pneumothorax: British Thoracic Society pleural disease guideline 2010. Thorax. 2010;65(SUPPL. 2).

De Leyn P, Lismonde M, Ninane V, et al. Belgian society of pneumology. Guidelines on the management of spontaneous pneumothorax. Acta Chir Belg. 2005;105(3):265–267.

Wang X, Wang L, Wang H, Zhang H. Simultaneous Bilateral Video-Assisted Thoracoscopic Surgery for the Treatment of Primary Spontaneous Pneumothorax. Cell Biochem Biophys. Springer US; 2015;71(3):1703–1708.

Bresticker MA, Oba J, LoCicero J, Greene R. Optimal pleurodesis: A comparison study. Ann Thorac Surg. The Society of Thoracic Surgeons; 1993;55(2):364–367.

Marjański T, Sowa K, Czapla A, Rzyman W. Catamenial pneumothorax - A review of the literature. Kardiochirurgia i Torakochirurgia Pol. 2016;13(2):117–121.

Vuong NL, Elshafay A, Thao LP, et al. Efficacy of treatments in primary spontaneous pneumothorax: A systematic review and network meta-analysis of randomized clinical trials. Respir Med. Elsevier; 2018;137(February):152–166.

Donatelli P, Trenatacosti F, Pellegrino MR, et al. Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia. BMC Pulm Med. BioMed Central; 2021;21(1):1–6.

Kurman JS. Persistent air leak management in critically ill patients. J Thorac Dis. 2021;13(8):5223–5231.

Thachuthara-George J. Pneumothorax in patients with respiratory failure in ICU. J Thorac Dis. 2021;13(8):5195–5204.

Brown SGA, Ball EL, Perrin K, et al. Conservative versus Interventional Treatment for Spontaneous Pneumothorax. N Engl J Med. 2020;382(5):405–415.

Kelly AM, Druda D. Comparison of size classification of primary spontaneous pneumothorax by three international guidelines: A case for international consensus? Respir Med. Elsevier Ltd; 2008;102(12):1830–1832.

Nikolić MZ, Lok LSC, Mattishent K, et al. Noninterventional statistical comparison of BTS and CHEST guidelines for size and severity in primary pneumothorax. Eur Respir J. 2015;45(6):1731–1734.

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