Medicinal Plants and Secondary Metabolites for Ocular Diseases
Referanslar
Süntar I. Importance of ethnopharmacological studies in drug discovery: role of medicinal plants. Phytochemistry Reviews. 2020;19(5):1199-209. doi: 10.1007/s11101-019-09629-9
Yapar EA, Durgun M, Esentürk I, et al. Herbal bioactives for ocular drug delivery systems. In: Bakshi IS, Bala R, Maadan R, Sindhu RK (eds.) Herbal Bioactive-Based Drug Delivery Systems. London: 2022 p. 25-61.
Semwal A, Kumar V, Bhatt SP, et al. Medicinal plants with antiocular activities. International Journal Medical Research. 2016;1(2):35-53.
Dorcas W, Emilliene E, Estella TF, et al. An Overview of herbal traditional eye care practices and the development of eye health promotion strategies in Cameroon. Journal of Advances in Medical and Pharmaceutical Sciences. 2019;2:1-16. doi: 10.1155/2013/617459
Chu KO, Pang CP. Herbal molecules in eye diseases. Taiwan Journal of Ophthalmology. 2014;4(3):103-109. doi: 10.1016/j.tjo.2014.03.005
Kaali R. Traditional eye medicines in Tanzania: Products, health risk awareness and safety evaluation. Archivos de Medicina. 2016;2(1):2. doi: 10.21767/2472-0151.10008
Pinheiro GKLO, Araújo Filho I, Araújo Neto I, et al. Nature as a source of drugs for ophthalmology. Arquivos Brasileiros de Oftalmologia. 2018;81:443-454. doi: 10.5935/0004-2749.20180086
Kels BD, Grzybowski A, Grant-Kels JM. Human ocular anatomy. Clinics in Dermatology. 2015;33(2):140-146. doi: 10.1016/j.clindermatol.2014.10.006
Urtti A. Challenges and obstacles of ocular pharmacokinetics and drug delivery. Advanced Drug Delivery Reviews. 2006;58(11):1131-1135. doi: 10.1016/j.addr.2006.07.027
Curto EM, Labelle A, Chandler HL. Aloe vera: an in vitro study of effects on corneal wound closure and collagenase activity. Veterinary Ophthalmology. 2014;17(6):403-10.
Laneri S, Di Lorenzo R, Bernardi A, et al. Aloe barbadensis: A plant of nutricosmetic interest. Natural Product Communications. 2020;15(7). doi: 10.1177/1934578X20932744
Woźniak A, Paduch R. Aloe vera extract activity on human corneal cells. Pharmaceutical Biology. 2012;50(2):147-54. doi: 10.3109/13880209.2011.579980
Cybulska A, Mozaffarieh M, Flammer J. Ginkgo biloba: an adjuvant therapy for progressive normal and high tension glaucoma. Molecular Vision. 2012;18:390.
Peris CS, Badaro E, Ferreira MA, et al. Color variation assay of the anthocyanins from Açai Fruit (Euterpe oleracea): a potential new dye for vitreoretinal surgery. Journal of Ocular Pharmacology and Therapeutics. 2013;29(8):746-753. doi: 10.1089/jop.2013.0003
Caiado RR, Peris CS, Lima-Filho AAS, et al. Retinal toxicity of acai fruit (euterpe oleracea) dye concentrations in rabbits: basic principles of a new dye for chromovitrectomy in humans. Current Eye Research. 2017;42(8):1185-1193. doi: 10.1080/02713683.2017.1297995
Chen J, Ferreira MA, Farah ME, et al. Posterior hyaloid detachment and internal limiting membrane peeling assisted by anthocyanins from acai fruit (Euterpe oleracea) and 10 other natural vital dyes: experimental study in cadaveric eyes. Retina. 2013;33(1):89-96. doi: 10.1097/IAE.0b013e3182618a6d
Bersanetti PA, Bueno TL, Morandim Giannetti AA, et al. Characterization of rabbit corneas subjected to stromal stiffening by the acai extract (Euterpe oleracea). Current Eye Research. 2017;42(4):528-533. doi: 10.1080/02713683.2016.1214970
Pinheiro Jr MN, Santos PMd, Santos RCRd, et al. Oral flaxseed oil (Linum usitatissimum) in the treatment for dry-eye Sjögren's syndrome patients. Arquivos Brasileiros de Oftalmologia. 2007;70:649-655. doi: 10.1590/S0004-27492007000400016
Ibrahim RB, Akolade JO, Aladodo RA, et al. Glucose and lipid lowering potentials of Heliotropium indicum L. leaves in alloxan-induced hyperglycaemic Rats. Notulae Scientia Biologicae. 2016;8(4):414-421. doi: 10.15835/nsb849850
Kyei S, Koffuor GA, Ramkissoon P, et al. Anti-glaucoma potential of Heliotropium indicum Linn in experimentally-induced glaucoma. Eye and Vision. 2015;2(1):1-8. doi: 10.1186/s40662-015-0027-1
Kyei S, Koffuor GA, Ramkissoon P, et al. Anti-inflammatory effect of Heliotropium indicum Linn on lipopolysaccharide-induced uveitis in New Zealand white rabbits. International Journal of Ophthalmology. 2016;9(4):528. doi: 10.18240/ijo.2016.04.08
Kyei S, Koffuor GA, Ramkissoon P, et al. Anti-cataract potential of Heliotropium indicum linn on galactose-induced cataract in sprague-dawley rats. Current Eye Research. 2017;42(3):394-401. doi: 10.1080/02713683.2016.1198486
Hurst JS, Bazan HE. The sensitivity of bovine corneal epithelial lyso-PAF acetyltransferase to cyclooxygenase and lipoxygenase inhibitors is independent of arachidonate metabolites. Journal of Ocular Pharmacology and Therapeutics. 1997;13(5):415-426. doi: 10.1089/jop.1997.13.415
Li S, Mao W, Du X, et al. Inhibition of rat lens aldose reductase by flavonoids-matteucinol and baicalein. Yan Ke Xue Bao. 1987;3(2):93-4, 137.
Nagaki Y, Hayasaka S, Zhang XY, et al. Effects of topical instillation of traditional herbal medicines, herbal extracts, and their components on prostaglandin E2-induced aqueous flare elevation in pigmented rabbits. Japanese Journal of Ophthalmology. 2003;47(3):249-253. doi: 10.1016/S0021-5155(03)00002-9
Wang H, Lau BWM, Wang Nl, et al. Lycium barbarum polysaccharides promotes in vivo proliferation of adult rat retinal progenitor cells. Neural Regeneration Research. 2015;10(12):1976. doi: 10.4103/1673-5374.172315
Qi B, Ji Q, Wen Y, et al. Lycium barbarum polysaccharides protect human lens epithelial cells against oxidative stress–induced apoptosis and senescence. PLoS One. 2014;9(10):e110275. doi: 10.1371/journal.pone.0110275
Song J, Li Y, Ge J, et al. Protective effect of bilberry (Vaccinium myrtillus L.) extracts on cultured human corneal limbal epithelial cells (HCLEC). Phytotherapy Research. 2010;24(4):520-524. doi: 10.1002/ptr.2974
Yao N, Lan F, He RR, et al. Protective effects of bilberry (Vaccinium myrtillus L.) extract against endotoxin-induced uveitis in mice. Journal of Agricultural and Food Chemistry. 2010;58(8):4731-4736. doi: 10.1021/jf904572a
Riva A, Togni S, Franceschi F, et al. The effect of a natural, standardized bilberry extract (Mirtoselect®) in dry eye: a randomized, double blinded, placebo-controlled trial. European Review for Medical and Pharmacological Sciences. 2017;21(10):2518-2525.
Matsunaga N, Imai S, Inokuchi Y, et al. Bilberry and its main constituents have neuroprotective effects against retinal neuronal damage in vitro and in vivo. Molecular Nutrition and Food Research. 2009;53(7):869-877. doi: 10.1002/mnfr.200800394
Bhatt PR, Pandya KB, Sheth NR. Camellia sinensis L: the medicinal beverage: a review. International Journal of Pharmaceutical Sciences Review and Research. 2010;3(2):6-9.
Gupta S, Halder N, Srivastava S, et al. Green tea (Camellia sinensis) protects against selenite-induced oxidative stress in experimental cataractogenesis. Ophthalmic Research. 2002;34(4):258-263. doi: 10.1159/000063881
Pandey S, Singh H, Mogra A. Evaluation of pharmacological and clinical prophylactic efficacy of scrofoloso-12 group of electrohomoeopathy medicine in eye disorder. Journal of Medicine and Healthcare. 2022;4(2): 1-6. doi: 10.47363/JMHC/2022(4)187
Babbar O, IB R. Effect of berberine chloride eye drops on clinically positive trachoma patients. Indian Journal of Medical Research. 1982;76:83-88.
Attele AS, Wu JA, Yuan C-S. Ginseng pharmacology: multiple constituents and multiple actions. Biochemical Pharmacology. 1999;58(11):1685-1693. doi: 10.1016/S0006-2952(99)00212-9
Kim NR, Kim JH, Kim CY. Effect of Korean red ginseng supplementation on ocular blood flow in patients with glaucoma. Journal of Ginseng Research. 2010;34(3):237-245. doi: 10.5142/jgr.2010.34.3.237
Zhang L, Dai SZ, Nie XD, et al. Effect of Salvia miltiorrhiza on retinopathy. Asian Pacific Journal of Tropical Medicine. 2013;6(2):145-149. doi: 10.1016/S1995-7645(13)60011-5
Zhu Q, Su G, Nie L, et al. Salvia miltiorrhiza extracts protect against retinal injury in a rat glaucoma model. Experimental and Therapeutic Medicine. 2014;7(6):1513-1515. doi: 10.3892/etm.2014.1632
Tai BH, Jung BY, Cuong NM, et al. Total peroxynitrite scavenging capacity of phenylethanoid and flavonoid glycosides from the flowers of Buddleja officinalis. Biological and Pharmaceutical Bulletin. 2009;32(12):1952-1956. doi: 10.1248/bpb.32.1952
Kim CS, Jo K, Lee IS, et al. Topical application of apricot kernel extract improves dry eye symptoms in a unilateral exorbital lacrimal gland excision mouse. Nutrients. 2016;8(11):750. doi: 10.3390/nu8110750
Hitoe S, Tanaka J, Shimoda H. MaquiBright™ standardized maqui berry extract significantly increases tear fluid production and ameliorates dry eye-related symptoms in a clinical pilot trial. Panminerva Medica. 2014;56(3):1-6.
Yuca H, Özbek H, Demirezer LÖ, et al. α-Glucosidase and α-amylase inhibitory potential of main compounds and drug candidates from Elaeagnus rhamnoides (L.) A. Nelson. Chemical Papers. 2022;76(2):913-922. doi: 10.1007/s11696-021-01904-4
Nakamura S, Kimura Y, Mori D, et al. Restoration of tear secretion in a murine dry eye model by oral administration of palmitoleic acid. Nutrients. 2017;9(4):364. doi: 10.3390/nu9040364
Kang SW, Kim K, Lee CH, et al. A standardized extract of Rhynchosia volubilis Lour. exerts a protective effect on benzalkonium chloride-induced mouse dry eye model. Journal of Ethnopharmacology. 2018;215:91-100. doi: 10.1016/j.jep.2017.12.041
Bigagli E, Cinci L, D'Ambrosio M, et al. Pharmacological activities of an eye drop containing Matricaria chamomilla and Euphrasia officinalis extracts in UVB-induced oxidative stress and inflammation of human corneal cells. Journal of Photochemistry and Photobiology B: Biology. 2017;173:618-625. doi: 10.1016/j.jphotobiol.2017.06.031
Yuca H. Capsicum annuum L. In: Gürağaç Dereli FT, Ilhan M, Belwal T (eds.) Novel Drug Targets With Traditional Herbal Medicines. Gewerbestrasse; 2022 p. 95-108. doi: 10.1007/978-3-031-07753-1
Shanmugham V, Subban R. Capsanthin from Capsicum annum fruits exerts anti‐glaucoma, antioxidant, anti‐inflammatory activity, and corneal pro‐inflammatory cytokine gene expression in a benzalkonium chloride‐induced rat dry eye model. Journal of Food Biochemistry. 2022:e14352. doi: 10.1111/jfbc.14352
Raju TN, Kanth VR, Lavanya K. Effect of methanolic extract of Allium sativum (AS) in delaying cataract in STZ-induced diabetic rats. Journal of Ocular Biology, Diseases, and Informatics. 2008;1(1):46-54. doi: 10.1007/s12177-008-9003-5
Stohs SJ, Hartman MJ. Review of the safety and efficacy of Moringa oleifera. Phytotherapy Research. 2015;29(6):796-804. doi: 10.1002/ptr.5325
Hossain MF, Numan SM, Khan SS, et al. Human consumption, nutritional value and health benefits of Moringa (Moringa oleifera Lam.): a review. International Journal of Community Medicine and Public Health. 2022;9(9):3599. doi: 10.18203/2394-6040.ijcmph20222229
Duncan G, Collison DJ. Role of the non-neuronal cholinergic system in the eye: a review. Life Sciences. 2003;72(18-19):2013-2019. doi: 10.1016/S0024-3205(03)00064-X
Galvis V, Tello A, Parra MM, et al. Topical atropine in the control of myopia. Medical Hypothesis, Discovery and Innovation in Ophthalmology. 2016;5(3):78.
Chua WH, Balakrishnan V, Chan YH, et al. Atropine for the treatment of childhood myopia. Ophthalmology. 2006;113(12):2285-2291.
Chia A, Lu QS, Tan D. Five-year clinical trial on atropine for the treatment of myopia 2: myopia control with atropine 0.01% eyedrops. Ophthalmology. 2016;123(2):391-399. doi: 10.1016/j.ophtha.2015.07.004
Bachu RD, Chowdhury P, AlSaedi ZH, et al. Ocular drug delivery barriers—role of nanocarriers in the treatment of anterior segment ocular diseases. Pharmaceutics. 2018;10(1):28. doi: 10.3390/pharmaceutics10010028
Kronschläger M, Löfgren S, Yu Z, et al. Caffeine eye drops protect against UV-B cataract. Experimental Eye Research. 2013;113:26-31. doi: 10.1016/j.exer.2013.04.015
Zhang S, Zhou R, Li B, et al. Caffeine preferentially protects against oxygen-induced retinopathy. The FASEB Journal. 2017;31(8):3334. doi: 10.1096/fj.201601285R
Imanshahidi M, Hosseinzadeh H. Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytotherapy Research. 2008;22(8):999-1012. doi: 10.1002/ptr.2399
Xia S, Ma L, Wang G, et al. In vitro Antimicrobial Activity and the Mechanism of Berberine Against Methicillin-Resistant Staphylococcus aureus Isolated from Bloodstream Infection Patients. Infection and Drug Resistance. 2022;15:1933. doi: 10.2147/IDR.S357077
Xu Y, Yang G, Jin W, et al. Effects of homoharringtonine liposomes and homoharringtonine solution on glaucoma filtration surgery in rabbits. Chinese Journal of Ophthalmology. 1998;34(4):304-7, 21.
Hepler RS, Frank IR. Marihuana smoking and intraocular pressure. Jama. 1971;217(10):1392. doi:10.1001/jama.1971.03190100074024
Sun X, Xu CS, Chadha N, et al. Focus: Addiction: Marijuana for Glaucoma: A Recipe for Disaster or Treatment? The Yale Journal of Biology and Medicine. 2015;88(3):265.
Kokona D, Georgiou PC, Kounenidakis M, et al. Endogenous and synthetic cannabinoids as therapeutics in retinal disease. Neural Plasticity. 2016;2016: 1-12. doi: 10.1155/2016/8373020
Nebrisi EE. Neuroprotective activities of curcumin in parkinson’s disease: A Review of the Literature. International Journal of Molecular Sciences. 2021;22(20):11248. doi: 10.3390/ijms222011248
Zheng D, Huang C, Huang H, et al. Antibacterial mechanism of curcumin: A review. Chemistry and Biodiversity. 2020;17(8):e2000171. doi: 10.1002/cbdv.202000171
Šudomová M, Hassan ST. Nutraceutical curcumin with promising protection against herpesvirus infections and their associated inflammation: mechanisms and pathways. Microorganisms. 2021;9(2):292. doi: 10.3390/microorganisms9020292
Abrahams S, Haylett WL, Johnson G, et al. Antioxidant effects of curcumin in models of neurodegeneration, aging, oxidative and nitrosative stress: A review. Neuroscience. 2019;406:1-21. doi: 10.1016/j.neuroscience.2019.02.020
Narayanan VS, Muddaiah S, Shashidara R, et al. Variable antifungal activity of curcumin against planktonic and biofilm phase of different candida species. Indian Journal of Dental Research. 2020;31(1):145.
Daily JW, Yang M, Park S. Efficacy of turmeric extracts and curcumin for alleviating the symptoms of joint arthritis: a systematic review and meta-analysis of randomized clinical trials. Journal of Medicinal Food. 2016;19(8):717-729. doi: 10.1089/jmf.2016.3705
Khan H, Ullah H, Nabavi SM. Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects. Food and Chemical Toxicology. 2019;124:182-191. doi: 10.1016/j.fct.2018.12.002
Keihanian F, Saeidinia A, Bagheri RK, et al. Curcumin, hemostasis, thrombosis, and coagulation. Journal of Cellular Physiology. 2018;233(6):4497-4511. doi: 10.1002/jcp.26249
Li H, Sureda A, Devkota HP, et al. Curcumin, the golden spice in treating cardiovascular diseases. Biotechnology Advances. 2020;38:107343. doi: 10.1016/j.biotechadv.2019.01.010
Den Hartogh DJ, Gabriel A, Tsiani E. Antidiabetic properties of curcumin II: evidence from in vivo studies. Nutrients. 2019;12(1):58. doi: 10.3390/nu12010058
Manarin G, Anderson D, Silva JM, et al. Curcuma longa L. ameliorates asthma control in children and adolescents: A randomized, double-blind, controlled trial. Journal of Ethnopharmacology. 2019;238:111882. doi: 10.1016/j.jep.2019.111882
Fereydouni N, Darroudi M, Movaffagh J, et al. Curcumin nanofibers for the purpose of wound healing. Journal of Cellular Physiology. 2019;234(5):5537-5554. doi: 10.1002/jcp.27362
White M, Pasupuleti V, Roman YM, et al. Oral turmeric/curcumin effects on inflammatory markers in chronic inflammatory diseases: a systematic review and meta-analysis of randomized controlled trials. Pharmacological Research. 2019;146:104280. doi: 10.1016/j.phrs.2019.104280
Saleh MM, Darwish ZE, El Nouaem MI, et al. Chemopreventive effect of green tea and curcumin in induced oral squamous cell carcinoma: An experimental study. Alexandria Dental Journal. 2020;45(3):74-80. doi:10.21608/ADJALEXU.2020.82700
Chung SH, Choi SH, Choi JA, et al. Curcumin suppresses ovalbumin-induced allergic conjunctivitis. Molecular Vision. 2012;18:1966.
Chen M, Hu DN, Pan Z, et al. Curcumin protects against hyperosmoticity-induced IL-1β elevation in human corneal epithelial cell via MAPK pathways. Experimental Eye Research. 2010;90(3):437-443. doi: 10.1016/j.exer.2009.12.004
Mrowicka M, Mrowicki J, Kucharska E, et al. Lutein and zeaxanthin and their roles in age-related macular degeneration-neurodegenerative disease. Nutrients. 2022;14(4):827. doi: 10.3390/nu14040827
Zeinali M, Zirak MR, Rezaee SA, et al. Immunoregulatory and anti-inflammatory properties of Crocus sativus (Saffron) and its main active constituents: A review. Iranian Journal of Basic Medical Sciences. 2019;22(4):334. doi: 10.22038/ijbms.2019.34365.8158
Li K, Li Y, Ma Z, et al. Crocin exerts anti-inflammatory and anti-catabolic effects on rat intervertebral discs by suppressing the activation of JNK. International Journal of Molecular Medicine. 2015;36(5):1291-1299. doi: 10.3892/ijmm.2015.2359
Assimopoulou A, Sinakos Z, Papageorgiou V. Radical scavenging activity of Crocus sativus L. extract and its bioactive constituents. Phytotherapy Research. 2005;19(11):997-1000. 10.1002/ptr.1749
Siddiqui MJ, Saleh MS, Basharuddin SNB, et al. Saffron (Crocus sativus L.): As an antidepressant. Journal of Pharmacy and Bioallied Sciences. 2018;10(4):173. doi: 10.4103/JPBS.JPBS_83_18
Hosseini A, Razavi BM, Hosseinzadeh H. Saffron (Crocus sativus) petal as a new pharmacological target: a review. Iranian Journal of Basic Medical Sciences. 2018;21(11):1091. doi: 10.22038/IJBMS.2018.31243.7529
Mousavi M, Baharara J, Shahrokhabadi K. The synergic effects of Crocus sativus L. and low frequency electromagnetic field on VEGFR2 gene expression in human breast cancer cells. Avicenna Journal of Medical Biotechnology. 2014;6(2):123.
Christodoulou E, Kadoglou N, Stasinopoulou M, et al. Crocus sativus L. aqueous extract reduces atherogenesis, increases atherosclerotic plaque stability and improves glucose control in diabetic atherosclerotic animals. Atherosclerosis. 2018;268:207-14. doi: 10.1016/j.atherosclerosis.2017.10.032
Fernández JA, Hoz R, Ramírez AI, et al. Beneficial effects of saffron (Crocus sativus L.) in ocular pathologies, particularly neurodegenerative retinal diseases. Neural Regeneration Research. 2020;15(8):1408. doi: 10.4103/1673-5374.274325
Nader M, Chahine N, Salem C, et al. Saffron (Crocus sativus) pretreatment confers cardioprotection against ischemia-reperfusion injuries in isolated rabbit heart. Journal of Physiology and Biochemistry. 2016;72(4):711-719. doi: 10.1007/s13105-016-0510-8
Yousefi Manesh H, Aghamollaei H, Dehpour AR, et al. The role of saffron in improvement of ocular surface disease in a mouse model of lacrimal gland excision-induced dry eye disease. Experimental Eye Research. 2022:109127. doi: 10.1016/j.exer.2022.109127
Miean KH, Mohamed S. Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants. Journal of Agricultural and Food Chemistry. 2001;49(6):3106-3112. doi: 10.1021/jf000892m
Jan R, Khan M, Asaf S. Bioactivity and therapeutic potential of kaempferol and quercetin: new insights for plant and human health. Plants 2022;11(9):2623. doi: 10.3390/plants11192623
AlAbbasi FA, Kazmi I. Therapeutic role of kaempferol and myricetin in streptozotocin induced diabetes synergistically via modulation in pancreatic amylase, glycogen storage and insulin secretion. Research Square. 2022. doi: 10.21203/rs.3.rs-1679223/v1 doi: 10.21203/rs.3.rs-1679223/v1
Yang W, Xie D, Liang Y, et al. Multi-responsive fibroin-based nanoparticles enhance anti-inflammatory activity of kaempferol. Journal of Drug Delivery Science and Technology. 2022;68:103025. doi: 10.1016/j.jddst.2021.103025
Felice MR, Maugeri A, De Sarro G, et al. Molecular pathways involved in the anti-cancer activity of flavonols: a focus on myricetin and kaempferol. International Journal of Molecular Sciences. 2022;23(8):4411. doi: 10.3390/ijms23084411
Chuang YL, Fang HW, Ajitsaria A, et al. Development of kaempferol-loaded gelatin nanoparticles for the treatment of corneal neovascularization in mice. Pharmaceutics. 2019;11(12):635. doi: 10.3390/pharmaceutics11120635
Zhao L, Wang H, Du X. The therapeutic use of quercetin in ophthalmology: Recent applications. Biomedicine and Pharmacotherapy. 2021;137:111371. doi: 10.1016/j.biopha.2021.111371
Ding Y, Li C, Zhang Y, et al. Quercetin as a Lyn kinase inhibitor inhibits IgE-mediated allergic conjunctivitis. Food and Chemical Toxicology. 2020;135:110924. doi: 10.1016/j.fct.2019.110924
He S, Stankowska DL, Ellis DZ, et al. Targets of neuroprotection in glaucoma. Journal of Ocular Pharmacology and Therapeutics. 2018;34(1-2):85-106. doi: 10.1089/jop.2017.0041
Semwal DK, Semwal RB, Combrinck S, et al. Myricetin: A dietary molecule with diverse biological activities. Nutrients. 2016;8(2):90. doi: 10.3390/nu8020090
Yin Y, Zong R, Bao X, et al. Oxidative stress suppresses cellular autophagy in corneal epithelium. Investigative Ophthalmology and Visual Science. 2018;59(8):3286-3293. doi: 10.1167/iovs.18-24057
Verma S, Dutta A, Dahiya A, et al. Quercetin-3-rutinoside alleviates radiation-induced lung inflammation and fibrosis via regulation of NF-κB/TGF-β1 signaling. Phytomedicine. 2022;99:154004. doi: 10.1016/j.phymed.2022.154004
Ola MS, Ahmed MM, Ahmad R, et al. Neuroprotective effects of rutin in streptozotocin-induced diabetic rat retina. Journal of Molecular Neuroscience. 2015;56(2):440-448.doi: 10.1007/s12031-015-0561-2
Salehi B, Fokou PVT, Sharifi Rad M, et al. The therapeutic potential of naringenin: a review of clinical trials. Pharmaceuticals. 2019;12(1):11. doi: 10.3390/ph12010011
Li Q, Wu X, Xin S, et al. Preparation and characterization of a naringenin solubilizing glycyrrhizin nanomicelle ophthalmic solution for experimental dry eye disease. European Journal of Pharmaceutical Sciences. 2021;167:106020. doi: 10.1016/j.ejps.2021.106020
Anwar S, Speciale A, Fratantonio D, et al. Cyanidin-3-O-glucoside modulates intracellular redox status and prevents HIF-1 stabilization in endothelial cells in vitro exposed to chronic hypoxia. Toxicology Letters. 2014;226(2):206-213.doi: 10.1016/j.toxlet.2014.01.048
Morimitsu Y, Kubota K, Tashiro T, et al. Inhibitory effect of anthocyanins and colored rice on diabetic cataract formation in the rat lenses. International Congress Series. 2002;1245:503-508. doi: 10.1016/S0531-5131(02)00919-6
Anthony K, Subramanya G, Uprichard S, et al. Antioxidant and anti-hepatitis c viral activities of commercial milk thistle food supplements. Antioxidants. 2013;2(1):23-36. doi: 10.3390/antiox2010023
Fallah Huseini H, Zaree A, Babaei Zarch A, et al. The effect of herbal medicine Silybum marianum (L.) Gaertn. seed extract on galactose induced cataract formation in rat. Journal of Medicinal Plants. 2004;3(12):58-62.
Jangid AK, Solanki R, Patel S, et al. Genistein encapsulated inulin-stearic acid bioconjugate nanoparticles: Formulation development, characterization and anticancer activity. International Journal of Biological Macromolecules. 2022;206:213-21. doi: 10.1016/j.ijbiomac.2022.02.031
Li C, Chen R, Xu M, et al. Hyaluronic acid modified MPEG-b-PAE block copolymer aqueous micelles for efficient ophthalmic drug delivery of hydrophobic genistein. Drug Delivery. 2018;25(1):1258-65. doi: 10.1080/10717544.2018.1474972
Teng Y, Cui H, Yang M, et al. Protective effect of puerarin on diabetic retinopathy in rats. Molecular Biology Reports. 2009;36(5):1129-33. doi: 10.1007/s11033-008-9288-2
Fathalipour M, Mahmoodzadeh A, Safa O, et al. Puerarin as potential treatment in diabetic retinopathy. Journal of Herbmed Pharmacology. 2020;9(2):105-11. doi: 10.34172/jhp.2020.14
AbuAmero KK, Kondkar AA, Chalam KV. Resveratrol and ophthalmic diseases. Nutrients. 2016;8(4):200. doi: 10.3390/nu8040200
Liu XQ, Wu BJ, Pan WH, et al. Resveratrol mitigates rat retinal ischemic injury: the roles of matrix metalloproteinase-9, inducible nitric oxide, and heme oxygenase-1. Journal of Ocular Pharmacology and Therapeutics. 2013;29(1):33-40. doi: 10.1089/jop.2012.0141
Kiso Y, Tohkin M, Hikino H, et al. Mechanism of antihepatotoxic activity of glycyrrhizin, I: effect on free radical generation and lipid peroxidation. Planta Medica. 1984;50(04):298-302. doi: 10.1055/s-2007-969714
Petrera E, Coto CE. Therapeutic effect of meliacine, an antiviral derived from Melia azedarach L., in mice genital herpetic infection. Phytotherapy Research. 2009;23(12):1771-7. doi: 10.1002/ptr.2850
Alché LE, Berra A, Veloso MJ, et al. Treatment with meliacine, a plant derived antiviral, prevents the development of herpetic stromal keratitis in mice. Journal of Medical Virology. 2000;61(4):474-80. doi: 10.1002/1096-9071(200008)61:4<474::AID-JMV10>3.0.CO;2-K
Pullaiah T. Pharmacology of Coleus forskohlii and Forskolin. Pullaiah T. (ed) In: Forskolin. Gewerbestrasse; 2022 p. 65-106. doi: 10.1007/978-981-19-6521-0_5
Caprioli J, Sears M. Forskolin lowers intraocular pressure in rabbits, monkeys, and man. The Lancet. 1983;321(8331):958-1960. doi: 10.1016/S0140-6736(83)92084-6
Ou S, Kwok KC. Ferulic acid: pharmaceutical functions, preparation and applications in foods. Journal of the Science of Food and Agriculture. 2004;84(11):1261-1269. doi: 10.1002/jsfa.1873
Chen HC, Chen ZY, Wang TJ, et al. Herbal supplement in a buffer for dry eye syndrome treatment. International Journal of Molecular Sciences. 2017;18(8):1697. doi: 10.3390/ijms18081697
Bai D, Liu K, He X, et al. Effect of dietary chlorogenic acid on growth performance, antioxidant function, and immune response of broiler breeders under immune stress and stocking density stress. Veterinary Sciences. 2022;9(10):582. doi: 10.3390/vetsci9100582
Song L, Yang H, Liang D, et al. A chlorogenic acid-loaded hyaluronic acid-based hydrogel facilitates anti-inflammatory and pro-healing effects for diabetic wounds. Journal of Drug Delivery Science and Technology. 2022;70:103232. doi: 10.1016/j.jddst.2022.103232
Singh AK, Rana HK, Singh V, et al. Evaluation of antidiabetic activity of dietary phenolic compound chlorogenic acid in streptozotocin induced diabetic rats: molecular docking, molecular dynamics, in silico toxicity, in vitro and in vivo studies. Computers in Biology and Medicine. 2021;134:104462. doi: 10.1016/j.compbiomed.2021.104462
Gupta A, Atanasov AG, Li Y, et al. Chlorogenic acid for cancer prevention and therapy: Current status on efficacy and mechanisms of action. Pharmacological Research. 2022:106505. doi: 10.1016/j.phrs.2022.106505
Shin JY, Sohn J, Park KH. Chlorogenic acid decreases retinal vascular hyperpermeability in diabetic rat model. Journal of Korean Medical Science. 2013;28(4):608-613. doi: 10.3346/jkms.2013.28.4.608