Alkil Sübstitüsyonunun Farmasötik Kimya Açısından Önemi

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Blass BE. Basic Principles of Drug Discovery and Development [Internet]. Saint Louis, UNITED STATES: Elsevier Science & Technology; 2015. Available from: http://ebookcentral.proquest.com/lib/ataturk-ebooks/detail.action?docID=2036170

Wermuth CG, Aldous D, Raboisson P, Rognan D. The Practice of Medicinal Chemistry [Internet]. San Diego, UNITED KINGDOM: Elsevier Science & Technology; 2015. Available from: http://ebookcentral.proquest.com/lib/ataturk-ebooks/detail.action?docID=2079962

Poole SK, Poole CF. Separation methods for estimating octanol–water partition coefficients. Journal of Chromatography B [Internet]. 2003;797(1):3–19. Available from: https://www.sciencedirect.com/science/article/pii/S1570023203006937

Di L, Kerns E, Di L, Kerns E. Drug-Like Properties: Concepts, Structure Design and Methods : From ADME to Toxicity Optimization [Internet]. Burlington, UNITED STATES: Elsevier Science & Technology; 2008. Available from: http://ebookcentral.proquest.com/lib/ataturk-ebooks/detail.action?docID=365589

Dearden JC. Partitioning and lipophilicity in quantitative structure-activity relationships. Environ Health Perspect [Internet]. 1985 Sep 1;61:203–28. Available from: https://doi.org/10.1289/ehp.8561203

Dalkara S, Saraç S. Yapı Aktivite İlişkileri. In: Akgün Hülya, Balkan Ayla, Bilgin Altan, Çalış Ünsal, Gökhan Nesrin, Dalkara Sevim, et al., editors. Farmasötik Kimya. Ankara: Hacettepe Yayınları; 2004. p. 73–108.

Balaz S. Modeling Kinetics of Subcellular Disposition of Chemicals. Chem Rev [Internet]. 2009 May 13;109(5):1793–899. Available from: https://doi.org/10.1021/cr030440j

Erckes V, Steuer C. A story of peptides, lipophilicity and chromatography – back and forth in time. RSC Med Chem [Internet]. 2022;13(6):676–87. Available from: http://dx.doi.org/10.1039/D2MD00027J

Di L, Kerns EH. Blood-Brain Barrier in Drug Discovery : Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs [Internet]. New York, UNITED STATES: John Wiley & Sons, Incorporated; 2015. Available from: http://ebookcentral.proquest.com/lib/ataturk-ebooks/detail.action?docID=1895601

Patrick GL. Medicinal Chemistry. Oxford: Oxford University Press; 2013.

Mukherjee SM, Singh SP, Kapoor RP, Dass R. Organic Chemistry [Internet]. Daryaganj, INDIA: New Age International Ltd; 2008. 25–45 p. Available from: http://ebookcentral.proquest.com/lib/ataturk-ebooks/detail.action?docID=3017383

Kar A. Medicinal Chemistry [Internet]. Daryaganj, INDIA: New Age International Ltd; 2007. 28–34 p. Available from: http://ebookcentral.proquest.com/lib/ataturk-ebooks/detail.action?docID=361141

Harrold MW, Zavod RM. Basic Concepts in Medicinal Chemistry [Internet]. Bethesda MD, USA: American Society of Health-System Pharmacists; 2018. Available from: https://publications.ashp.org/view/book/9781585286027/9781585286027.xml

Pasternak GW, Pan YX. Mu Opioids and Their Receptors: Evolution of a Concept. Sibley DR, editor. Pharmacol Rev [Internet]. 2013 Oct 1;65(4):1257. Available from: http://pharmrev.aspetjournals.org/content/65/4/1257.abstract

Harrold MW, Zavod RM. Basic Concepts in Medicinal Chemistry [Internet]. Bethesda MD, USA: American Society of Health-System Pharmacists; 2018. Available from: https://publications.ashp.org/view/book/9781585286027/9781585286027.xml

Bilgin AA. Steroit Hormonlar. In: Hülya A, Ayla B, Altan B, Ünsal Ç, Nesrin G, Sevim D, et al., editors. Farmasötik Kimya. Ankara: Hacettepe Yayınları; 2004. p. 671–730.

Neal MJ. Medical Pharmacology at a Glance [Internet]. Newark, UNITED STATES: John Wiley & Sons, Incorporated; 2015. Available from: http://ebookcentral.proquest.com/lib/ataturk-ebooks/detail.action?docID=7104207

Balkan A. Kolinerjik İlaçlar. In: Hülya A, Ayla B, Altan B, Ünsal Ç, Nesrin G, Sevim D, et al., editors. Farmasötik Kimya. Ankara: Hacettepe Yayınları; 2004. p. 490–500.

Strosberg AD. 3 Adrenoreceptor [Internet]. London, UNITED KINGDOM: Taylor & Francis Group; 2000. Available from: http://ebookcentral.proquest.com/lib/ataturk-ebooks/detail.action?docID=181231

Kar A. Medicinal Chemistry [Internet]. Daryaganj, INDIA: New Age International Ltd; 2007. 377–395 p. Available from: http://ebookcentral.proquest.com/lib/ataturk-ebooks/detail.action?docID=361141

Balkan A. Adrenerjik İlaçlar. In: Hülya A, Ayla B, Altan B, Ünsal Ç, Nesrin G, Sevim D, et al., editors. Farmasötik Kimya. Ankara: Hacettepe Yayınları; 2004. p. 456–60.

Sun S, Fu J. Methyl-containing pharmaceuticals: Methylation in drug design. Bioorg Med Chem Lett [Internet]. 2018;28(20):3283–9. Available from: https://www.sciencedirect.com/science/article/pii/S0960894X18307479

Duggan KC, Walters MJ, Musee J, Harp JM, Kiefer JR, Oates JA, et al. Molecular Basis for Cyclooxygenase Inhibition by the Non-steroidal Anti-inflammatory Drug Naproxen*. Journal of Biological Chemistry [Internet]. 2010;285(45):34950–9. Available from: https://www.sciencedirect.com/science/article/pii/S0021925820470358

Xu S, Rouzer CA, Marnett LJ. Oxicams, a class of nonsteroidal anti-inflammatory drugs and beyond. IUBMB Life [Internet]. 2014 Dec 1;66(12):803–11. Available from: https://doi.org/10.1002/iub.1334

Kaehler ST, Phleps W, Hesse E. Dexibuprofen: pharmacology, therapeutic uses and safety. Inflammopharmacology [Internet]. 2003;11(4):371–83. Available from: https://doi.org/10.1163/156856003322699555

van ZPA. Pharmacology of centrally acting hypotensive drugs. Br J Clin Pharmacol [Internet]. 1980 Feb 1;10(S1):13S-20S. Available from: https://doi.org/10.1111/j.1365-2125.1980.tb04899.x

Whitfield AC, Moore BT, Daniels RN. Classics in Chemical Neuroscience: Levodopa. ACS Chem Neurosci [Internet]. 2014 Dec 17;5(12):1192–7. Available from: https://doi.org/10.1021/cn5001759

Adcock I, Chung KF, Chung PPKF. Overcoming Steroid Insensitivity in Respiratory Disease [Internet]. Chichester, UNITED KINGDOM: John Wiley & Sons, Incorporated; 2008. Available from: http://ebookcentral.proquest.com/lib/ataturk-ebooks/detail.action?docID=366789

Blobaum AL, Marnett LJ. Molecular Determinants for the Selective Inhibition of Cyclooxygenase-2 by Lumiracoxib*. Journal of Biological Chemistry [Internet]. 2007;282(22):16379–90. Available from: https://www.sciencedirect.com/science/article/pii/S0021925820649584

García-González CM, Baker J. Treatment of early rheumatoid arthritis: Methotrexate and beyond. Curr Opin Pharmacol [Internet]. 2022;64:102227. Available from: https://www.sciencedirect.com/science/article/pii/S1471489222000546

Armstrong SC, Cozza KL. Antihistamines. Psychosomatics [Internet]. 2003;44(5):430–4. Available from: https://www.sciencedirect.com/science/article/pii/S0033318203702588

Beermann B, Hellström K, Rosén A. Gastrointestinal absorption of certain anticholinergic drugs. Eur J Clin Pharmacol [Internet]. 1972;5(2):87–92. Available from: https://doi.org/10.1007/BF00561751

Palaska E. Trankilizan İlaçlar. In: Hülya A, Ayla B, Altan B, Ünsal Ç, Nesrin G, Sevim D, et al., editors. Farmasötik Kimya. Ankara: Hacettepe Yayınları; 2004. p. 264–329.

Barreiro EJ, Kümmerle AE, Fraga CAM. The Methylation Effect in Medicinal Chemistry. Chem Rev [Internet]. 2011 Sep 14;111(9):5215–46. Available from: https://doi.org/10.1021/cr200060g

Manna D, Roy G, Mugesh G. Antithyroid Drugs and Their Analogues: Synthesis, Structure, and Mechanism of Action. Acc Chem Res [Internet]. 2013 Nov 19;46(11):2706–15. Available from: https://doi.org/10.1021/ar4001229

Ruffolo RRJr, Bondinell W, Hieble JP. .alpha.- and .beta.-Adrenoceptors: From the Gene to the Clinic. 2. Structure-Activity Relationships and Therapeutic Applications. J Med Chem [Internet]. 1995 Sep 1;38(19):3681–716. Available from: https://doi.org/10.1021/jm00019a001

Ertan M, Tozkoparan B. Kinolonlar. In: Hülya A, Ayla B, Altan B, Ünsal Ç, Nesrin G, Sevim D, et al., editors. Farmasötik Kimya. Ankara: Hacettepe Yayınları; 2004. p. 1079–93.

Zhang GF, Zhang S, Pan B, Liu X, Feng LS. 4-Quinolone derivatives and their activities against Gram positive pathogens. Eur J Med Chem [Internet]. 2018;143:710–23. Available from: https://www.sciencedirect.com/science/article/pii/S0223523417309856

Erdoğan H. Analjezik İlaçlar. In: Hülya A, Ayla B, Altan B, Ünsal Ç, Nesrin G, Sevim D, et al., editors. Farmasötik Kimya. Ankara: Hacettepe Yayınları; 2004. p. 413–4.

Goldberg JS. Stereochemical Basis for a Unified Structure Activity Theory of Aromatic and Heterocyclic Rings in Selected Opioids and Opioid Peptides. Perspect Medicin Chem [Internet]. 2010 Jan 1;4:PMC.S3898. Available from: https://doi.org/10.4137/PMC.S3898

Methadone [Internet]. DrugBank. [cited 2023 Feb 22]. Available from: https://go.drugbank.com/drugs/DB00333

Yu G, Maskray V, Jackson SH, Swift CG, Tiplady B. A comparison of the central nervous system effects of caffeine and theophylline in elderly subjects. Br J Clin Pharmacol [Internet]. 1991 Sep 1;32(3):341–5. Available from: https://doi.org/10.1111/j.1365-2125.1991.tb03909.x