QT Prolongation and Psychotropic Medications

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Girardin FR, Gex-Fabry M, Berney P, et al. Drug-induced long QT in adult psychiatric inpatients: the 5-year cross-sectional ECG Screening Outcome in Psychiatry study. American Journal of Psychiatry. 2013;170(12):1468-76. Doi: 10.1176/appi.ajp.2013.12060860

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Beach SR, Kostis WJ, Celano CM, et al. Meta-analysis of selective serotonin reuptake inhibitorassociated QTc prolongation. The Journal of Clinical Psychiatry. 2014;75(5):e441-9. Doi: 10.4088/JCP.13r08672

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Wang Y, Nomikos GG, Karim A, et al. Effect of Vortioxetine on Cardiac Repolarization in Healthy Adult Male Subjects: Results of a Thorough QT/QTc Study. Clinical pharmacology in drug development. 2013;2(4):298-309. DOI: 10.1002/cpdd.51

Noordam R, van den Berg ME, Niemeijer MN, et al. Assessing Prolongation of the Heart Rate Corrected QT Interval in Users of Tricyclic Antidepressants: Advice to Use Fridericia Rather Than Bazett's Correction. Journal of clinical psychopharmacology. 2015;35(3):260-5 DOI: 10.1097/JCP.0000000000000321

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Funk MC, Beach SR, Bostwick JR, et al. QTc prolongation and psychotropic medications. American Journal of Psychiatry. 2020; 177(3), 273-274. Doi: 10.1176/appi.ajp.2019.1760501

Girardin FR, Gex-Fabry M, Berney P, et al. Drug-induced long QT in adult psychiatric inpatients: the 5-year cross-sectional ECG Screening Outcome in Psychiatry study. American Journal of Psychiatry. 2013;170(12):1468-76. Doi: 10.1176/appi.ajp.2013.12060860

Lin CH, Chen CH, Wang SY, et al. Predictive factors for QTc prolongation in schizophrenic patients taking antipsychotics. Journal of the Formosan Medical Association= Taiwan yi zhi. 2004; 103(6), 437-441.

Thomas D, Wu K, Kathöfer S, et al. The antipsychotic drug chlorpromazine inhibits HERG potassium channels. British journal of pharmacology. 2003; 139(3), 567-574. doi.org/10.1038/sj.bjp.0705283