Rat Karaciğer Dokusunda Retinol (Vitamin A) Ve Α-Tokoferolün (Vitamin E) Floresans Dedektörlü Ultra Performanslı Sıvı Kromatografisi (Uplc-Fd) ile Eş Zamanlı Miktar Analizi

Plozza T, Trenerry VC, and Caridi D, The simultaneous determination of vitamins A, E and β-carotene in bovine milk by high performance liquid chromatography–ion trap mass spectrometry (HPLC–MSn). Food Chemistry; 2012; 134(1): p. 559-563. doi: 10.1016/j.foodchem.2012.02.121

Karmi O, Zayed A, Baraghethi S, et al., Measurement of vitamin B12 concentration: A review on available methods. IIOAB J; 2011; 2(2): p. 23-32.

Köseoğlu K, Ulusoy Hİ, Yilmaz E, et al., Simple and sensitive determination of vitamin A and E in the milk and egg yolk samples by using dispersive solid phase extraction with newly synthesized polymeric material. Journal of Food Composition and Analysis; 2020; 90: p. 103482. doi: 10.1016/j.jfca.2020.103482

Statovci D, Aguilera M, MacSharry J, et al., The impact of western diet and nutrients on the microbiota and immune response at mucosal interfaces. Frontiers in immunology; 2017; 8: p. 838. doi: 10.3389/fimmu.2017.00838

Semba RD, Vitamin A, immunity, and infection. Clinical Infectious Diseases; 1994; 19(3): p. 489-499. doi: 10.1093/clinids/19.3.489

Silveira ER and Moreno FS, Natural retinoids and β-carotene: from food to their actions on gene expression. The Journal of Nutritional Biochemistry; 1998; 9(8): p. 446-456. doi: 10.1016/S0955-2863(98)00040-0

Traber MG and Sies H, Vitamin E in humans: demand and delivery. Annual review of nutrition; 1996; 16(1): p. 321-347. doi: 10.1146/annurev.nu.16.070196.001541

DeMan J, Finley J, Hurst W, et al. Principles of food chemistry. 4 th. ed. New York: Springer International Publishing; 2018.

Flynn A, Hirvonen T, Mensink GB, et al., Intake of selected nutrients from foods, from fortification and from supplements in various European countries. Food & nutrition research; 2009; 53(1): p. 2038. doi: 10.3402/fnr.v53i0.2038

Liao C-M and Lin C-M, Life course effects of socioeconomic and lifestyle factors on metabolic syndrome and 10-year risk of cardiovascular disease: A longitudinal study in Taiwan adults. International journal of environmental research and public health; 2018; 15(10): p. 2178. doi: 10.3390/ijerph15102178

Ayasan T and Karakozak E, Hayvan beslemede β-karoten kullanılması ve etkileri. Kafkas Üniversitesi Veteriner Fakültesi Dergisi; 2010; 16(4). doi: 10.9775/kvfd.2010.2008

Brozos C, Kiossis E, Fthenakis G, et al., Supplementation of lactating ewes with a glucogenic preparation or β-carotene in mid-to late lactation, on subsequent milk yield and luteinizing hormone secretion. Canadian journal of animal science; 2007; 87(2): p. 185-190. doi: 10.4141/A06-080

Woollard DC, Bensch A, Indyk H, et al., Determination of vitamin A and vitamin E esters in infant formulae and fortified milk powders by HPLC: Use of internal standardisation. Food chemistry; 2016; 197: p. 457-465. doi: 10.1016/j.foodchem.2015.10.077

Yu Z, Zhang F, Xu C, et al., Association between circulating antioxidants and longevity: insight from Mendelian randomization study. BioMed Research International; 2022; 2022. doi: 10.1155/2022/4012603

Aboul-Soud MA, Al-Othman AM, El-Desoky GE, et al., Hepatoprotective effects of vitamin E/selenium against malathion-induced injuries on the antioxidant status and apoptosis-related gene expression in rats. The Journal of toxicological sciences; 2011; 36(3): p. 285-296. doi: 10.2131/jts.36.285

Tyśkiewicz K, Dębczak A, Gieysztor R, et al., Determination of fat‐and water‐soluble vitamins by supercritical fluid chromatography: a review. Journal of Separation Science; 2018; 41(1): p. 336-350. doi: 10.1002/jssc.201700598

Ataman MB, Aköz M, Dönmez N, et al., The investigation of the effects of vitamin A, vitamin E, and β-carotene plus vitamin E on some fertility parameters in ewes. Tropical Animal Health and Production; 2023; 55(3): p. 175. doi: 10.1007/s11250-023-03586-4

Yazlik MO, Olgac KT, Colakoglu HE, et al., Effects of vitamin B-1, vitamin E and selenium on pregnancy and blood metabolites profile during non-breeding season and early prediction of pregnancy by thermographic monitoring in Merino ewes. Indian Journal of Animal Sciences; 2020; 90(10): p. 1368-1372. doi: 10.56093/ijans.v90i10.111306

Della Pepa G, Vetrani C, Lombardi G, et al., Isocaloric dietary changes and non-alcoholic fatty liver disease in high cardiometabolic risk individuals. Nutrients; 2017; 9(10): p. 1065. doi: 10.3390/nu9101065

Rodriguez Amado JR, Lafourcade Prada A, Escalona Arranz JC, et al., Antioxidant and hepatoprotective activity of a new tablets formulation from Tamarindus indica L. Evidence-Based Complementary and Alternative Medicine; 2016; 2016. doi: 10.1155/2016/3918219

Heiser M, Hutter-Paier B, Jerkovic L, et al. Vitamin E binding protein A famin Protects Neuronal Cells in vitro. In: Kurt A. Jellinger RS, Manfred Windisch (eds.). Ageing and Dementia Current and Future Concepts. Vienna: Springer; 2002. p. 337-345.

Halliwell B, Antioxidants in human health and disease. Annual review of nutrition; 1996; 16(1): p. 33-50. doi: 10.1146/annurev.nu.16.070196.000341

Kardinaal AF, Van'T Veer P, Kok F, et al., Antioxidants in adipose tissue and risk of myocardial infarction: the EURAMIC study. The Lancet; 1993; 342(8884): p. 1379-1384. doi: 10.1016/0140-6736(93)92751-E

Oliver M, Antioxidant nutrients, atherosclerosis, and coronary heart disease. British heart journal; 1995; 73(4): p. 299. doi: 10.1136/hrt.73.4.299

McEligot AJ, Rock CL, Flatt SW, et al., Plasma carotenoids are biomarkers of long-term high vegetable intake in women with breast cancer. The Journal of nutrition; 1999; 129(12): p. 2258-2263. doi: 10.1093/jn/129.12.2258

Jha P, Flather M, Lonn E, et al., The antioxidant vitamins and cardiovascular disease: a critical review of epidemiologic and clinical trial data. Annals of Internal Medicine; 1995; 123(11): p. 860-872. doi: 10.7326/0003-4819-123-11-199512010-00009

Liu Z, Kang X, and Fang F, Solid phase extraction with electrospun nanofibers for determination of retinol and α-tocopherol in plasma. Microchimica Acta; 2010; 168: p. 59-64. doi: 10.1007/s00604-009-0263-y

Yamini Y, Tahmasebi E, and Ranjbar L, Magnetic nanoparticle-based solid-phase extraction of vitamin B 12 from pharmaceutical formulations. Biological trace element research; 2012; 147: p. 378-385. doi: 10.1007/s12011-011-9299-z

Ramadan M and Mörsel J-T, Direct isocratic normal-phase HPLC assay of fat-soluble vitamins and β-carotene in oilseeds. European Food Research and Technology; 2002; 214: p. 521-527. doi: 10.1007/s00217-002-0511-4

Andersen LF, Solvoll K, Johansson LR, et al., Evaluation of a food frequency questionnaire with weighed records, fatty acids, and alpha-tocopherol in adipose tissue and serum. American journal of epidemiology; 1999; 150(1): p. 75-87. doi: 10.1093/oxfordjournals.aje.a009921

Barua A, Olson J, Furr H, et al. Vitamin A and carotenoids. In: De Leenheer AP, Lambert W, Van Bocxlaer JF (eds.). Modern chromatographic analysis of vitamins: Revised and expanded. 3rd ed. Boca Raton: CRC Press; 2000. p. 8-75.

Nollet LM. Handbook of Food Analysis: Volume 1: Physical Characterization and Nutrient Analysis. 2nd ed. Boca Raton: CRC Press; 2004.

Cavina G, Gallinella B, Porra R, et al., Carotenoids, retinoids and alpha-tocopherol in human serum: identification and determination by reversed-phase HPLC. Journal of pharmaceutical and biomedical analysis; 1988; 6(3): p. 259-269. doi: 10.1016/0731-7085(88)80052-9

Thurnham D, Smith E, and Flora PS, Concurrent liquid-chromatographic assay of retinol, alpha-tocopherol, beta-carotene, alpha-carotene, lycopene, and beta-cryptoxanthin in plasma, with tocopherol acetate as internal standard. Clinical chemistry; 1988; 34(2): p. 377-381. doi: 10.1093/clinchem/34.2.377

Bui MH, Simple determination of retinol, α-tocopherol and carotenoids (lutein, all-trans-lycopene, α-and β-carotenes) in human plasma by isocratic liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications; 1994; 654(1): p. 129-133. doi: 10.1016/0378-4347(93)E0441-R

Panfili G, Manzi P, and Pizzoferrato L, High-performance liquid chromatographic method for the simultaneous determination of tocopherols, carotenes, and retinol and its geometric isomers in Italian cheeses. Analyst; 1994; 119(6): p. 1161-1165. doi: 10.1039/AN9941901161

Epler KS, Ziegler RG, and Craft NE, Liquid chromatographic method for the determination of carotenoids, retinoids and tocopherols in human serum and in food. Journal of Chromatography B: Biomedical Sciences and Applications; 1993; 619(1): p. 37-48. doi: 10.1016/0378-4347(93)80444-9

Aaran RK and Nikkari T, HPLC method for the simultaneous determination of beta-carotene, retinol and alpha-tocopherol in serum. Journal of Pharmaceutical and Biomedical Analysis; 1988; 6(6): p. 853-857. doi: 10.1016/0731-7085(88)80101-8

ICH, International Conference on Harmonisation of technical requirements for registration of pharmaceuticals for human use, in validation of analytical procedures: text and methodology Q2 (R1). 2005. p. 05.

Çapa M. (2017). Hippophae Rhamnoides (Çalı Gagası) ve Juniperus Drupacea (Andız) Bitkilerinin Çeşitli Ekstrelerinin Antioksidan Aktivitelerinin Araştırılması. (Tez No: 487653). Atatürk Üniversitesi Sağlık Bilimleri Enstitüsü (Eczacılık Fakültesi), Erzurum.