Pediyatrik Kalp Hastaliklarında Tanı Yöntemleri

Authors

Fuat Laloğlu

Synopsis

The diagnostic process in pediatric cardiology begins with a detailed patient history, physical examination, chest radiography, pulse oximetry, and blood pressure measurements. While pregnancy, birth, medication, and family history are thoroughly questioned during history taking, physical examination evaluates cyanosis, murmurs, peripheral pulses, precordium, organomegaly, and rashes. Chest radiography provides basic information regarding cardiothoracic ratio, cardiac contour, and pulmonary vascularity, whereas pulse oximetry is a mandatory criterion for screening critical cyanotic congenital heart diseases in the early neonatal period. Inter-extremity blood pressure measurement is used to detect coarctation of the aorta, while 24-hour ambulatory blood pressure monitoring is utilized to identify white coat hypertension and nocturnal blood pressure load. Electrocardiography (ECG), 24-hour Holter ECG, event recorders, and invasive electrophysiological studies play a critical role in diagnosing rhythm and conduction disorders. Echocardiography (TTE, TEE, Fetal, and Stress Echo) serves as the primary non-invasive imaging modality to evaluate cardiac chambers, valves, cardiac shunts, and functions. Exercise testing is preferred for evaluating ischemia and exercise capacity, whereas the tilt table test is chosen to evaluate vasovagal syncope. Computed tomography and magnetic resonance imaging depict complex anatomical and vascular anomalies radiation-free or with high resolution, while cardiac catheterization and angiography provide detailed hemodynamic data and interventional treatment options. Additionally, specific biochemical markers such as troponin, NT-proBNP, and CRP complement the diagnostic and follow-up processes.

References

Johnson WH, Moller JH (Eds.). (2014). Pediatric Cardiology: The Essential Pocket Guide (3rd ed.,pp.1-73). Hoboken: Wiley-Blackwell.

Cassidy SC, Allen HD, Phillips JR. (2016). History and Physical Examination. Hugh D. Allen, Robert E. Shaddy, Daniel J. Penny,Timothy F. Feltes, Frank Cetta (Eds.), Moss & Adams' Heart Disease in Infants, Children, and Adolescents, Including the Fetus and Young Adult (pp. 250-261).China:Lippincott Williams & Wilkins.

Ertuğrul İ, Özkutlu S.(2017). Kalp Hastalıklarında Tanı. Murat Yurdakök (Ed.). Yurdakök Pediatri (s.2975-2980). Ankara: Güneş Tıp Kitapevleri.

Ertuğrul T, Ömeroğlu RE, Dindar A, Aydoğan Ü, Nişli K. (2010). Kalp-Damar Sisteminin Değerlendirilmesi. Olcay Neyzi, Türkan Ertuğrul (Eds.), Pediyatri (s.1131-1155). İstanbul: Nobel Tıp Kitabevleri.

Park MK. (2014). Park's Pediatric Cardiology for Practitioners. (pp.314-318). Philadelphia: Elsevier Saunders.

Ahmad H, Chowdhury D.(2018). Neonatal Screening for Heart Disease. Jonathan N. Johnson, Deepak M. Kamat (Eds.), Common Cardiac Issues in Pediatrics (pp. 197-204). USA: American Academy of Pediatrics.

Martin GR, Ewer AK, Gaviglio A, et al. Updated Strategies for Pulse Oximetry Screening for Critical Congenital Heart Disease. Pediatrics. 2020 Jul;146(1):e20191650. doi: 10.1542/peds.2019-1650.

Kemper AR, Mahle WT, Martin GR, et al. Strategies for implementing screening for critical congenital heart disease. Pediatrics. 2011;128(5):e1259–e1267.

Hsu DT, Gersony WM. (2014). Assessment of the Cardiac Patient: History and Physical Examination. Eduardo da Cruz, Dunbar Ivy, James Jaggers (Eds.), Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care (pp.303-315). London: Springer.

Park MK. (2014). Park's Pediatric Cardiology for Practitioners. (pp.184-205). Philadelphia: Elsevier Saunders.

Park MK. (2014). Park's Pediatric Cardiology for Practitioners. (pp.77-116). Philadelphia: Elsevier Saunders.

Ali US, Ohri A. (2013). Systemic Hypertension in Children. Kumar RK, Prabhu SS, Ahamed MZ (Eds.). Pediatric Cardiology (IAP Speciality Series) (pp. 95-108).India: Jaypee Brothers Medical Publishers.

Park M, Guntheroth W. (2006).How to Read Pediatric ECGs. (4th ed.). USA: Mosby.

Van Hare GF, Silva JNA. (2016). The Normal Electrocardiogram. Hugh D. Allen, Robert E. Shaddy, Daniel J. Penny,Timothy F. Feltes, Frank Cetta (Eds.), Moss & Adams' Heart Disease in Infants, Children, and Adolescents, Including the Fetus and Young Adult (pp. 548-565).China:Lippincott Williams & Wilkins.

Fogoros RN. (2006). Electrophysiologic Testing (4th Ed.). USA: Wiley-Blackwell.

de Bakker JMT, Vos MA. (2012). Methodological and Technical Considerations. Shenasa M, Hindricks G, Borggrefe M, Breithardt G, Josephson ME (Eds.). Cardiac Mapping (pp. 3-11). UK: Wiley-Blackwell.

Kelle AM, Qureshi MY. (2018). The Role of Echocardiography. Jonathan N. Johnson, Deepak M. Kamat (Eds.), Common Cardiac Issues in Pediatrics (pp. 49-70). USA: American Academy of Pediatrics.

Ayabakan C. (2017). Ekokardiyografi. Murat Yurdakök (Ed.). Yurdakök Pediatri (s.2992-3002). Ankara: Güneş Tıp Kitapevleri.

Miller OI, Bell AJ, Simpson JM. (2016). Transesophageal and Intraoperative Echocardiography. Lai WW, Mertens LL, Cohen MS, Geva T (Eds.), Echocardiography in Pediatric and Congenital Heart Disease: From Fetus to Adult (pp.777-790). UK: Wiley-Blackwell.

Johnson WH, Moller JH (Eds.). (2014). Pediatric Cardiology: The Essential Pocket Guide (pp.1-72). Hoboken: Wiley-Blackwell.

Donofrio MT, Moon-Grady AJ, Hornberger LK, et al. American Heart Association Adults With Congenital Heart Disease Joint Committee of the Council on Cardiovascular Disease in the Young and Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and Council on Cardiovascular and Stroke Nursing. Diagnosis and treatment of fetal cardiac disease: A scientific statement from the American Heart Association. Circulation. 2014;129:2183–2242.

Araujo JJ. Stress Echocardiography in Pediatric and Adult Congenital Heart Disease: A Complement in Anatomical and Functional Assessment. Curr Probl Cardiol. 2021 Mar;46(3):100762. doi: 10.1016/j.cpcardiol.2020.100762.

Ciliberti P, McLeod I, Cairello F, et al. Semi-supine exercise stress echocardiography in children and adolescents: feasibility and safety. Pediatr Cardiol. 2015 Mar;36(3):633-9. doi: 10.1007/s00246-014-1058-4.

Morrical B, Johnson JN. (2018). Basics of Exercise Testing. Jonathan N. Johnson, Deepak M. Kamat (Eds.), Common Cardiac Issues in Pediatrics (pp. 71-78). USA: American Academy of Pediatrics.

Park MK. (2014). Park's Pediatric Cardiology for Practitioners. (pp.505-515). Philadelphia: Elsevier Saunders.

Bernstein D. (2020). Laboratory Cardiac Evaluation. Robert M. Kliegman, Joseph W. St. Geme (Eds.), Nelson Textbook of Pediatrics (pp. 2354-2367). Kanada: Elsevier.

Krishnamurthy R, Golriz F, Jadhav S. (2016). Cardiac Computed Tomography in Children with Congenital Heart Disease. Hugh D. Allen, Robert E. Shaddy, Daniel J. Penny,Timothy F. Feltes, Frank Cetta (Eds.), Moss & Adams' Heart Disease in Infants, Children, and Adolescents, Including the Fetus and Young Adult (pp. 413-437).China:Lippincott Williams & Wilkins.

Meadows AK, Dae MW. (2011). Radiologic Imaging. Rudolph CD, Rudolph AM, Lister GE, First L, Gershon AA. (Eds.), Rudolph's Pediatrics (pp.1873-1887 ). USA: McGraw-Hill Education.

Geva T, Powell AJ. (2016). Magnetic Resonance Imaging. Hugh D. Allen, Robert E. Shaddy, Daniel J. Penny,Timothy F. Feltes, Frank Cetta (Eds.), Moss & Adams' Heart Disease in Infants, Children, and Adolescents, Including the Fetus and Young Adult (pp. 374-413).China:Lippincott Williams & Wilkins.

Mc Mahon CJ, Eidem BW, Bezold LI, et al. Is cardiac catheterization a prerequisite in all patients undergoing bidirectional cavopulmonary anastomosis? J Am Soc Echocardiogr. 2003 Oct;16(10):1068-72. doi: 10.1016/S0894-7317(03)00592-3.

Ro PS, Rychik J, Cohen MS, et al. Diagnostic assessment before Fontan operation in patients with bidirectional cavopulmonary anastomosis: are noninvasive methods sufficient? J Am Coll Cardiol. 2004 Jul 7;44(1):184-7. doi: 10.1016/j.jacc.2004.02.058.

Sun RR, Lu L, Liu M, et al. Biomarkers and heart disease. Eur Rev Med Pharmacol Sci. 2014 Oct;18(19):2927-35.

Hauser JA, Demyanets S, Rusai K, et aI. Diagnostic performance and reference values of novel biomarkers of paediatric heart failure. Heart. 2016 Oct 15;102(20):1633-9. doi: 10.1136/heartjnl-2016-309460.

Piek A, Du W, de Boer RA, et al. Novel heart failure biomarkers: why do we fail to exploit their potential? Crit Rev Clin Lab Sci. 2018 Jun;55(4):246-263. doi: 10.1080/10408363.2018.1460576.

Published

May 17, 2021

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