Geriatrik Hastalarda Preoperatif Değerlendirme ve Peroperatif Anestezi Yönetimi
Synopsis
Due to the increase in life expectancy, the demand for surgery and anesthesia in geriatric patients is rising, making the careful management of anatomical and physiological changes, chronic diseases, and polypharmacy imperative. To minimize perioperative and postoperative mortality and morbidity rates, a detailed history should be taken prior to surgery; during this process, the patient's nutritional, cardiovascular, respiratory, renal, and neurological conditions, past surgeries, allergies, smoking and alcohol use, as well as social support and intensive care requirements must be evaluated holistically. In physical examination, the Mallampati score and thyromental distance should be assessed to anticipate potential difficult intubation, systemic examinations should be completed, and the ASA classification system should be used for risk stratification. Before elective procedures, fasting guidelines of six to eight hours must be followed, and perioperative fluid management should be meticulously planned to prevent dehydration and renal failure. While central and peripheral blocks reduce the risk of postoperative delirium and thromboembolism, general anesthesia is preferred in patients with severe cardiovascular disease. Since the requirement for intravenous anesthetics decreases in the elderly, drugs should be administered slowly and titrated, while sevoflurane and desflurane, which provide hemodynamic stability and rapid recovery, should be selected for maintenance. Maintaining body temperature during the peroperative period, rigorously monitoring hemodynamics, and preventing blood pressure fluctuations play a critical role in preventing the development of postoperative delirium. In postoperative pain management, paracetamol stands out as the primary and reliable option, whereas opioid medications, which carry a high risk of respiratory depression, must be administered with extreme caution.
References
Barnett SR. Preoperative Assessment of Older Adults.Anesthesiol Clin. 2019 Sep;37(3):423-436. Doi: 10.1016/j.anclin.2019.04.003
Roth D, Pace NL, Lee A et al. Airway physical examination tests for detection of difficult airway management in apparently normal adult patients. Cochrane Database Syst Rev. 2018 May 15;5:CD008874. Doi: 10.1002/14651858. CD008874.
Hopkins TJ, Raghunathan K, Barbeito A et al. Associations between ASA physical status and postoperative mortality at 48 h: a contemporary dataset analysis compared to a historical cohort. Perioper Med (Lond). 2016 Oct 20;5:29. eCollection 2016. Doi:10.1186/s13741-016-0054-z
Knittel JG, Wildes TS. Preoperative Assessment of Geriatric Patients. Anesthesiol Clin. 2016 Mar;34(1):171-83. Doi: 10.1016/j.anclin.2015.10.013.
Steinmetz J, Rasmussen LS. The elderly and general anesthesia. Minerva Anestesiol 2010; 76: 745-52.
Nishi T, Maeda T, Imatoh T et al. Comparison of regional with general anesthesia on mortality and perioperative length of stay in older patients after hip fracture surgery. Int J Qual Health Care. 2018 Nov 17. Doi: 10.1093/intqhc/mzy233.
Levine WC, Mehta V, Landesberg G. Anesthesia for the elderly: selected topics. Curr Opin Anaesthesiol 2006;19:320-4. Doi:10.1097/01.aco.0000192807.63785.59
Liu LL, Wiener-Kronish JP. Perioperative anesthesia issues in the elderly. Crit Care Clin 2003;19:641-56 Doi:10.1016/s0749-0704(03)00058-7
Iannuzzi E, Iannuzzi M, Viola G et al. Desflurane and sevoflurane in elderly patients during general anesthesia: a double blind comparison. Minerva Anestesiol 2005;71:147-55
Lebanidze NG, Peshkov TG. [Recovery after low-flow anesthesia in elderly patients]. Georgian Med News 2006:63-5
Moppett IK, Rowlands M, Mannings Aet al. LiDCO-based fluid management in patients undergoing hip fracture surgery under spinal anaesthesia: A randomized trial and systematic review. Br J Anaesth 2015; 114: 444-59. Doi:10.1093/bja/aeu386
Hamilton MA, Cecconi M, Rhodes A. A systematic review and meta-analysis on the use of preemptive hemodynamic intervention to improve postoperative outcomes in moderate and high-risk surgical patients. Anesth Analg 2011; 112: 1392-402. Doi:10.1213/ANE.0b013e3181eeaae5
Chun EH, Lee GY, Kim CH. Postoperative hypothermia in geriatric patients undergoing arthroscopic shoulder surgery. Anesth Pain Med 2019; 14: 112-6. Doi: 10.17085/apm.2019.14.1.112
Sandner-Kiesling A, List WF. [Anesthesia related physiologic and pharmacologic changes in the elderly]. Anaesthesiol Reanim 2003;28:60-8
Kojima Y, Narita M. Postoperative outcome among elderly patients after general anesthesia. Acta Anaesthesiol Scand 2006; 50:19-25. Doi:10.1111/j.1399-6576.2005.00882.x
Freye E, Levy JV. [Use of opioids in the elderly pharmacokinetic and pharmacodynamic considerations]. Anasthesiol Intensivmed Notfallmed Schmerzther 2004;39:527-37.Doi:10.1055/s-2004-825883
Nishikawa K, Kimura S, Shimodate Y et al. A comparison of intravenousbased and epidural-based techniques for anesthesia and postoperative analgesia in elderly patients undergoing laparoscopic cholecystectomy J Anesth 2007;21:1-6.Doi: 10.1007/s00540-006-0459-9
Langer T, Santini A, Zadek F et al.Intraoperative hypotension is not associated with postoperative cognitive dysfunction in elderly patients undergoing general anesthesia for surgery: results of a randomized controlled pilot trial. J Clin Anesth. 2019 Feb;52:111-118. Doi: 10.1016/j.jclinane.2018.09.021.
Hirsch J, DePalma G, Tsai TT et al. Impact of intraoperative hypotension and blood pressure fluctuations on early postoperative delirium after non-cardiac surgery. Br J Anaesth. 2015 Sep;115(3):418-26. Doi: 10.1093/bja/aeu458.